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Quantitative comparison of single-cell RNA sequencing versus single-molecule RNA imaging for quantifying transcriptional noise.

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第一作者： Neha,Khetan

第一单位： Gladstone

作者： Neha,Khetan ^[1] ; Binyamin,Zuckerman ^[2] ; Giuliana P,Calia ^[1] ; Xinyue,Chen ^[2] ; Ximena Garcia,Arceo ^[1] ; Leor S,Weinberger ^[2]

作者单位： Gladstone ^[1] UCSF Center for Cell Circuitry, University of California, San Francisco, CA 94158. ^[2] UCSF Center for Cell Circuitry, University of California, San Francisco, CA 94158.;Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158.;Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158.;Lead contact. ^[3]

关键词 noise-enhancer molecule single molecule RNA FISH (smFISH)single-cell RNA sequencing (scRNA-seq)transcriptional noise

DOI 10.1101/2024.08.09.607289

PMID 39149226

发布时间 2024-10-23

基金项目

K12 GM081266/GM/NIGMS NIH HHS/United States R37 AI109593/AI/NIAID NIH HHS/United States S10 OD017993/OD/NIH HHS/United States S10 OD028511/OD/NIH HHS/United States

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Quantitative comparison of single-cell RNA sequencing versus single-molecule RNA imaging for quantifying transcriptional noise.

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Quantitative comparison of single-cell RNA sequencing versus single-molecule RNA imaging for quantifying transcriptional noise.

bioRxiv

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