A computer-aided, heterodimer-based "triadic" carrier-free drug delivery platform to mitigate multidrug resistance in lung cancer and enhance efficiency.

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第一作者： Liyan,Yang

第一单位： School of Physics and Physical Engineering, Qufu Normal University, Qufu 273165, PR China; Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. Electronic address: yangly@iccas.ac.cn.

作者： Liyan,Yang ^[1] ; Yingying,Zhang ^[2] ; Yuxin,Lai ^[2] ; Wenjing,Xu ^[3] ; Shizeng,Lei ^[3] ; Guixiang,Chen ^[3] ; Zhonglei,Wang ^[4]

作者单位： School of Physics and Physical Engineering, Qufu Normal University, Qufu 273165, PR China; Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. Electronic address: yangly@iccas.ac.cn. ^[1] School of Physics and Physical Engineering, Qufu Normal University, Qufu 273165, PR China. ^[2] Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, PR China. ^[3] Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, PR China; School of Pharmaceutical Sciences, Key Laboratory of Bioorganic Phosphorus, Chemistry & Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, PR China. Electronic address: wangzl16@tsinghua.org.cn. ^[4]

关键词 CUR@CPT-SS-ERI NPs Computer-aided DTX@ERL-SS-CPT NPs Heterodimers Multidrug resistance “Triadic” drug delivery platform