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A review of the physiological effects of microgravity and innovative formulation for space travelers.

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第一作者： Jey Kumar,Pachiyappan

第一单位： Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, The Nilgiris, 643001, Tamil Nadu, India.

作者： Jey Kumar,Pachiyappan ^[1] ; Manali,Patel ^[2] ; Parikshit,Roychowdhury ^[1] ; Imrankhan,Nizam ^[1] ; Raagul,Seenivasan ^[1] ; Swathi,Sudhakar ^[3] ; M R,Jeyaprakash ^[4] ; Veera Venkata Satyanarayana Reddy,Karri ^[1] ; Jayakumar,Venkatesan ^[5] ; Priti,Mehta ^[6] ; Sudhakar,Kothandan ^[1] ; Indhumathi,Thirugnanasambandham ^[1] ; Gowthamarajan,Kuppusamy ^[7]

作者单位： Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, The Nilgiris, 643001, Tamil Nadu, India. ^[1] Department of Pharmaceutical Analysis, Institute of Pharmacy, Nirma University, Ahmedabad, Gujarat, 382481, India. ^[2] Department of Applied Mechanics and Biomedical Engineering, Indian Institute of Technology Madras, Chennai, 600036, India. ^[3] Department of Pharmaceutical Analysis, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, The Nilgiris, 643001, Tamil Nadu, India. ^[4] CEO, Harpy Aerospace International Private Limited, Chennai, 600056, Tamil Nadu, India. ^[5] Department of Pharmaceutical Analysis, Institute of Pharmacy, Nirma University, Ahmedabad, Gujarat, 382481, India. drpritimehta@nirmauni.ac.in. ^[6] Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, The Nilgiris, 643001, Tamil Nadu, India. gowthamsang@jssuni.edu.in. ^[7]

关键词 Dosage forms Fluid shift Medicine effect Pharmacokinetic and pharmacodynamic Space travel Stability Weightlessness

医学主题词人类(Humans);宇宙飞行(Space Flight);失重(Weightlessness);宇航员(Astronauts);药用制剂(Pharmaceutical Preparations);药物调剂(Drug Compounding)

DOI 10.1007/s10928-024-09938-3

PMID 39162918

发布时间 2024-11-21

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