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The Off-Treatment Effects of Olpasiran on Lipoprotein(a) Lowering: OCEAN(a)-DOSE Extension Period Results.

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第一作者： Michelle L,O'Donoghue

第一单位： TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. Electronic address: modonoghue@bwh.harvard.edu.

作者： Michelle L,O'Donoghue ^[1] ; Robert S,Rosenson ^[2] ; J Antonio G,López ^[3] ; Norman E,Lepor ^[4] ; Seth J,Baum ^[5] ; Elmer,Stout ^[6] ; Daniel,Gaudet ^[7] ; Beat,Knusel ^[3] ; Julia F,Kuder ^[8] ; Sabina A,Murphy ^[8] ; Huei,Wang ^[3] ; You,Wu ^[3] ; Trupti,Shah ^[3] ; Jingying,Wang ^[3] ; Tomasz,Wilmanski ^[3] ; Winnie,Sohn ^[3] ; Helina,Kassahun ^[3] ; Marc S,Sabatine ^[8] ; OCEAN(a)-DOSE Trial Investigators

作者单位： TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. Electronic address: modonoghue@bwh.harvard.edu. ^[1] Icahn School of Medicine, Mount Sinai Hospital, New York, New York, USA. ^[2] Global Development, Amgen, Thousand Oaks, California, USA. ^[3] David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA. ^[4] Flourish Research, Boca Raton, Florida, USA; Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida, USA. ^[5] Crossroads Clinical Research Inc, Mooresville, North Carolina, USA. ^[6] Department of Medicine, University of Montréal, Chicoutimi, Quebec, Canada. ^[7] TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. ^[8]

关键词 RNA interference atherosclerotic cardiovascular disease clinical trial lipoprotein(a)small interfering RNA