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首页> Toxicology in vitro : an international journal published in association with BIBRA> Unveiling the anticancer potential of Pestalotioprolide E, an unexplored macrolide: Targeting TRXR1-TRX1-ASK1-P38 signaling cascade in triple-negative breast cancer.

Unveiling the anticancer potential of Pestalotioprolide E, an unexplored macrolide: Targeting TRXR1-TRX1-ASK1-P38 signaling cascade in triple-negative breast cancer.

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作者： Ruma,Sarkar ^[1] ; Debobrata,Paul ^[2] ; Akash,Chatterjee ^[3] ; Anindita,Bhattacharya ^[3] ; Sayantan,Pradhan ^[3] ; Rajib Kumar,Goswami ^[4] ; Prosenjit,Sen ^[5]

作者单位： School of Biological Science, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India; B. D. Patel Institute of Paramedical Sciences, Charotar University of Science and Technology, CHARUSAT Campus, Changa 388421, Gujarat, India. ^[1] School of Chemical Science, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India. ^[2] School of Biological Science, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India. ^[3] School of Chemical Science, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India. Electronic address: ocrkg@iacs.res.in. ^[4] School of Biological Science, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India. Electronic address: bcps@iacs.res.in. ^[5]

关键词 Apoptosis Breast cancer Metastasis Pestalotioprolide E Thioredoxin reductase

主题词人类(Humans);细胞系, 肿瘤(Cell Line, Tumor);抗肿瘤药(Antineoplastic Agents);大环内酯类(Macrolides);硫氧还蛋白还原酶1(Thioredoxin Reductase 1);信号传导(Signal Transduction);硫氧还蛋白质类(Thioredoxins);细胞凋亡(Apoptosis);MAP激酶激酶激酶5(MAP Kinase Kinase Kinase 5);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases);细胞运动(Cell Movement);女(雌)性(Female)

DOI 10.1016/j.tiv.2024.105920

PMID 39173682

发布时间 2024-09-13

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