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Glutamine Supplementation as a Novel Metabolic Therapeutic Strategy for LIG3-Dependent Chronic Intestinal Pseudo-Obstruction.

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第一作者： Chiara,Diquigiovanni

第一单位： Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.

作者： Chiara,Diquigiovanni ^[1] ; Nicola,Rizzardi ^[2] ; Erica,Cataldi-Stagetti ^[1] ; Livia,Gozzellino ^[1] ; Federica,Isidori ^[3] ; Francesca,Valenti ^[2] ; Arianna,Orsini ^[1] ; Annalisa,Astolfi ^[4] ; Tania,Giangregorio ^[3] ; Loris,Pironi ^[4] ; Elisa,Boschetti ^[5] ; Serena,Arrigo ^[6] ; Alessandra,Maresca ^[7] ; Penelope,Magnoni ^[7] ; Anna,Costanzini ^[8] ; Valerio,Carelli ^[9] ; Mariko,Taniguchi-Ikeda ^[10] ; Romana,Fato ^[2] ; Christian,Bergamini ^[11] ; Roberto,De Giorgio ^[12] ; Elena,Bonora ^[4]

作者单位： Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy. ^[1] Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy. ^[2] Istituto di Ricovero e Cura a Carattere Scientifico, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. ^[3] Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy; Istituto di Ricovero e Cura a Carattere Scientifico, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. ^[4] Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy. ^[5] Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Giannina Gaslini, Genova, Italy. ^[6] Istituto di Ricovero e Cura a Carattere Scientifico, Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, Italy. ^[7] Department of Translational Medicine, University of Ferrara, Ferrara, Italy. ^[8] Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy; Istituto di Ricovero e Cura a Carattere Scientifico, Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, Italy. ^[9] Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, Aichi, Japan. ^[10] Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy. Electronic address: christian.bergamini2@unibo.it. ^[11] Department of Translational Medicine, University of Ferrara, Ferrara, Italy. Electronic address: dgrrrt@unife.it. ^[12]

关键词 Chronic Intestinal Pseudo-Obstruction L-Glutamine LIG3 Mitochondria