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首页> Proceedings of the National Academy of Sciences of the United States of America> A potential role for RNA aminoacylation prior to its role in peptide synthesis.

A potential role for RNA aminoacylation prior to its role in peptide synthesis.

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第一作者： Aleksandar,Radakovic

第一单位： HHMI, Department of Chemistry, The University of Chicago, Chicago, IL 60637.;Department of Genetics, Harvard Medical School, Boston, MA 02115.

作者： Aleksandar,Radakovic ^[1] ; Anna,Lewicka ^[2] ; Marco,Todisco ^[3] ; Harry R M,Aitken ^[4] ; Zoe,Weiss ^[5] ; Shannon,Kim ^[3] ; Abdullah,Bannan ^[5] ; Joseph A,Piccirilli ^[6] ; Jack W,Szostak ^[3]

作者单位： HHMI, Department of Chemistry, The University of Chicago, Chicago, IL 60637.;Department of Genetics, Harvard Medical School, Boston, MA 02115. ^[1] Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637. ^[2] HHMI, Department of Chemistry, The University of Chicago, Chicago, IL 60637. ^[3] HHMI, Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114.;Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138. ^[4] Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138. ^[5] HHMI, Department of Chemistry, The University of Chicago, Chicago, IL 60637.;Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637. ^[6]

关键词 RNA World T-loop aminoacylation ribozymes

主题词氨基酰化(Aminoacylation);RNA, 催化(RNA, Catalytic);核酸构象(Nucleic Acid Conformation);肽生物合成(Peptide Biosynthesis);甘氨酸(Glycine);RNA(RNA);肽类(Peptides);RNA, 转移(RNA, Transfer);蛋白质生物合成(Protein Biosynthesis);转移RNA氨酰化(Transfer RNA Aminoacylation);氨基酸类(Amino Acids)

DOI 10.1073/pnas.2410206121

PMID 39178230

发布时间 2024-09-01

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Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America

2024年121卷35期

e2410206121页

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Proceedings of the National Academy of Sciences of the United States of America

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Proceedings of the National Academy of Sciences of the United States of America

2024年121卷35期

e2410206121页

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