ITCH inhibits alkaliptosis in human pancreatic cancer cells through YAP1-dependent SLC16A1 activation.
作者:
主题词
人类(Humans);胰腺肿瘤(Pancreatic Neoplasms);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);转录因子(Transcription Factors);细胞系, 肿瘤(Cell Line, Tumor);衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);协同转运子(Symporters);泛素化(Ubiquitination);细胞死亡(Cell Death);阻遏蛋白质类(Repressor Proteins);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);癌, 胰腺管(Carcinoma, Pancreatic Ductal);氢离子浓度(Hydrogen-Ion Concentration);细胞增殖(Cell Proliferation)
DOI
10.1016/j.biocel.2024.106646
PMID
39179170
发布时间
2024-09-16
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