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Machine learning approaches to detect hepatocyte chromatin alterations from iron oxide nanoparticle exposure.

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第一作者： Jovana,Paunovic Pantic

第一单位： Department of Pathophysiology, Faculty of Medicine, University of Belgrade, Dr. Subotica 9, 11129, Belgrade, Serbia.

作者： Jovana,Paunovic Pantic ^[1] ; Danijela,Vucevic ^[1] ; Tatjana,Radosavljevic ^[1] ; Peter R,Corridon ^[2] ; Svetlana,Valjarevic ^[3] ; Jelena,Cumic ^[4] ; Ljubisa,Bojic ^[5] ; Igor,Pantic ^[6]

作者单位： Department of Pathophysiology, Faculty of Medicine, University of Belgrade, Dr. Subotica 9, 11129, Belgrade, Serbia. ^[1] Department of Immunology and Physiology, College of Medicine and Health Sciences, Khalifa University of Science and Technology, PO Box 127788, Abu Dhabi, UAE. peter.corridon@ku.ac.ae.;Department of Biomedical Engineering, Healthcare Engineering Innovation Center, Khalifa University of Science and Technology, PO Box 127788, Abu Dhabi, UAE. peter.corridon@ku.ac.ae.;Center for Biotechnology, Khalifa University of Science and Technology, PO Box 127788, Abu Dhabi, UAE. peter.corridon@ku.ac.ae.;Department of Biomedical Engineering and Biotechnology, College of Medicine and Health Sciences, Khalifa University of Science and Technology, PO Box 127788, Abu Dhabi, UAE. peter.corridon@ku.ac.ae. ^[2] Faculty of Medicine, Clinical Hospital Center Zemun, University of Belgrade, Vukova 9, 11000, Belgrade, Serbia. ^[3] Faculty of Medicine, University of Belgrade, University Clinical Centre of Serbia, Dr. Koste Todorovića 8, 11129, Belgrade, Serbia. ^[4] Institute for Artificial Intelligence Research and Development of Serbia, Fruškogorska 1, 21000, Novi Sad, Serbia. ^[5] Department of Medical Physiology, Faculty of Medicine, University of Belgrade, Visegradska 26/II, 11129, Belgrade, Serbia. igor.pantic@med.bg.ac.rs.;University of Haifa, 199 Abba Hushi Blvd, Mount Carmel, 3498838, Haifa, Israel. igor.pantic@med.bg.ac.rs.;Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105, Be'er Sheva, Israel. igor.pantic@med.bg.ac.rs.;Department of Pharmacology, College of Medicine and Health Sciences, Khalifa University of Science and Technology, PO Box 127788, Abu Dhabi, UAE. igor.pantic@med.bg.ac.rs. ^[6]

关键词 Gradient boosting Machine learning Nucleus Random forest Toxicology

医学主题词肝细胞(Hepatocytes);动物(Animals);染色质(Chromatin);小鼠(Mice);肝(Liver);正铁化合物(Ferric Compounds);男(雄)性(Male)

DOI 10.1038/s41598-024-70559-4

PMID 39179629

发布时间 2024-08-26

基金项目

RC2-2018-022 (HEIC)/Khalifa University of Science, Technology and Research 7739645/Science Fund of the Republic of Serbia

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交