Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted/founder sensitivity to broadly neutralizing antibodies.

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作者： Durgadevi,Parthasarathy ^[1] ; Karunakar Reddy,Pothula ^[2] ; Sneha,Ratnapriya ^[1] ; Héctor,Cervera Benet ^[1] ; Ruth,Parsons ^[3] ; Xiao,Huang ^[2] ; Salam,Sammour ^[2] ; Katarzyna,Janowska ^[2] ; Miranda,Harris ^[1] ; Joseph,Sodroski ^[4] ; Priyamvada,Acharya ^[5] ; Alon,Herschhorn ^[6]

作者单位： Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, USA. ^[1] Duke Human Vaccine Institute, Duke University, Durham, NC, USA. ^[2] Duke Human Vaccine Institute, Duke University, Durham, NC, USA.;Department of Biochemistry, Duke University, Durham, NC, USA. ^[3] Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.;Department of Microbiology, Harvard Medical School, Boston, MA, USA. ^[4] Duke Human Vaccine Institute, Duke University, Durham, NC, USA.;Department of Biochemistry, Duke University, Durham, NC, USA.;Department of Surgery, Duke University, Durham, NC, USA. ^[5] Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, USA. aherschh@umn.edu.;Institute for Molecular Virology, University of Minnesota, University of Minnesota, Minneapolis, MN, USA. aherschh@umn.edu.;Microbiology, Immunology, and Cancer Biology Graduate Program, University of Minnesota, Minneapolis, MN, USA. aherschh@umn.edu.;The College of Veterinary Medicine Graduate Program, University of Minnesota, Minneapolis, MN, USA. aherschh@umn.edu.;Molecular Pharmacology and Therapeutics Graduate Program, University of Minnesota, Minneapolis, MN, USA. aherschh@umn.edu. ^[6]