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A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.

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第一作者: Matei A,Banu
第一单位: Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.
作者单位: Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA. [1] Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA. [2] Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA. [3] Spanish National Center for Cardiovascular Research, Madrid, Spain. [4] Department of Neurological Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, USA. [5] Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA. [6] Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.;Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA. [7] Department of Biological Sciences, Department of Chemistry and Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA. [8] Department of Neurological Surgery, UCLA Geffen School of Medicine, Los Angeles, CA, USA. [9] Sulzberger Columbia Genome Center, Columbia University, New York, NY, USA. [10] NCI Neuro-oncology Branch, Bethesda, MD, USA. [11] University of Illinois Cancer Center, Department of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, USA. [12] Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA. pas2182@cumc.columbia.edu. [13] Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA. pc561@cumc.columbia.edu.;Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA. pc561@cumc.columbia.edu. [14]
DOI 10.1038/s44318-024-00176-4
PMID 39192032
发布时间 2024-11-13
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