Analysis of Cytotoxic Granules and Constitutively Produced Extracellular Vesicles from Large Granular Lymphocytic Leukemia Cell Lines.

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第一作者： Lara,Ploeger

第一单位： Molecular Immunology-Institute for Immunology, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.

作者： Lara,Ploeger ^[1] ; Patrick,Kaleja ^[2] ; Andreas,Tholey ^[2] ; Marcus,Lettau ^[3] ; Ottmar,Janssen ^[1]

作者单位： Molecular Immunology-Institute for Immunology, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany. ^[1] Systematic Proteomics & Bioanalytics-Institute for Experimental Medicine, University of Kiel, 24105 Kiel, Germany. ^[2] Stem Cell Transplantation and Immunotherapy-Internal Medicine II, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany. ^[3]

关键词 NK cells T cells cytotoxic effector proteins cytotoxic granules exosomes extracellular vesicles (EV)large granular lymphocyte leukemia (LGLL)lysosome-related effector vesicles (LREV)proteomics profiling

主题词人类(Humans);白血病, 大颗粒淋巴细胞(Leukemia, Large Granular Lymphocytic);细胞系, 肿瘤(Cell Line, Tumor);细胞质颗粒(Cytoplasmic Granules);溶酶体(Lysosomes);蛋白质组学(Proteomics);杀伤细胞, 天然(Killer Cells, Natural);穿孔素(Perforin);颗粒酶类(Granzymes);抗原, 分化, T淋巴细胞(Antigens, Differentiation, T-Lymphocyte)

DOI 10.3390/cells13161310

PMID 39195200

发布时间 2025-01-24

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2024年13卷16期

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Analysis of Cytotoxic Granules and Constitutively Produced Extracellular Vesicles from Large Granular Lymphocytic Leukemia Cell Lines.

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Analysis of Cytotoxic Granules and Constitutively Produced Extracellular Vesicles from Large Granular Lymphocytic Leukemia Cell Lines.

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