High-throughput transcriptomics toxicity assessment of eleven data-poor bisphenol A alternatives.

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作者： Marc A,Beal ^[1] ; Melanie C,Coughlan ^[2] ; Andrée,Nunnikhoven ^[2] ; Matthew,Gagné ^[3] ; Tara S,Barton-Maclaren ^[3] ; Lauren M,Bradford ^[4] ; Andrea,Rowan-Carroll ^[4] ; Andrew,Williams ^[4] ; Matthew J,Meier ^[4]

作者单位： Bureau of Chemical Safety, Health Products and Food Branch, Health Canada, Canada. Electronic address: marc.beal@hc-sc.gc.ca. ^[1] Bureau of Chemical Safety, Health Products and Food Branch, Health Canada, Canada. ^[2] Existing Substances Risk Assessment Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Canada. ^[3] Environmental Health Science and Research Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Canada. ^[4]

关键词 Bisphenol A Endocrine disruption MCF-7 New approach methodologies Regrettable substitutions Toxicogenomics

主题词酚类(Phenols);二苯甲基化合物(Benzhydryl Compounds);人类(Humans);内分泌干扰物(Endocrine Disruptors);雌激素受体α(Estrogen Receptor alpha)

DOI 10.1016/j.envpol.2024.124827

PMID 39197648

发布时间 2024-10-29

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准确一般字义偏差语意偏离译文作用小提交