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Structural basis for CCR6 modulation by allosteric antagonists.

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第一作者： David Jonathan,Wasilko

第一单位： Discovery Sciences, Medicine Design, Pfizer Inc., Groton, CT, USA.

作者： David Jonathan,Wasilko ^[1] ; Brian S,Gerstenberger ^[2] ; Kathleen A,Farley ^[1] ; Wei,Li ^[3] ; Jennifer,Alley ^[3] ; Mark E,Schnute ^[2] ; Ray J,Unwalla ^[2] ; Jorge,Victorino ^[1] ; Kimberly K,Crouse ^[3] ; Ru,Ding ^[3] ; Parag V,Sahasrabudhe ^[1] ; Fabien,Vincent ^[1] ; Richard K,Frisbie ^[1] ; Alpay,Dermenci ^[4] ; Andrew,Flick ^[4] ; Chulho,Choi ^[4] ; Gary,Chinigo ^[4] ; James J,Mousseau ^[4] ; John I,Trujillo ^[4] ; Philippe,Nuhant ^[2] ; Prolay,Mondal ^[4] ; Vincent,Lombardo ^[4] ; Daniel,Lamb ^[5] ; Barbara J,Hogan ^[5] ; Gurdeep Singh,Minhas ^[6] ; Elena,Segala ^[6] ; Christine,Oswald ^[6] ; Ian W,Windsor ^[1] ; Seungil,Han ^[1] ; Mathieu,Rappas ^[5] ; Robert M,Cooke ^[6] ; Matthew F,Calabrese ^[1] ; Gabriel,Berstein ^[3] ; Atli,Thorarensen ^[2] ; Huixian,Wu ^[7]

作者单位： Discovery Sciences, Medicine Design, Pfizer Inc., Groton, CT, USA. ^[1] Medicine Design, Pfizer Inc., Cambridge, MA, USA. ^[2] Inflammation and Immunology Research, Pfizer Inc., Cambridge, MA, USA. ^[3] Medicine Design, Pfizer Inc., Groton, CT, USA. ^[4] Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge, UK.;Nxera Pharma UK Limited, Steinmetz Building, Granta Park, Great Abington, Cambridge, UK. ^[5] Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge, UK. ^[6] Discovery Sciences, Medicine Design, Pfizer Inc., Groton, CT, USA. huixian.wu@pfizer.com. ^[7]