The evolutionary features and roles of single nucleotide variants and charged amino acid mutations in influenza outbreaks during NPI period.

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第一作者： Zhong-Zhou,Huang

第一单位： Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.;School of Public Health, Sun Yat-Sen University, Guangzhou, 510080, China.;Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Center for Disease Control and Prevention, Guangzhou, 511430, China.

作者： Zhong-Zhou,Huang ^[1] ; Jing,Tan ^[2] ; Ping,Huang ^[3] ; Bai-Sheng,Li ^[4] ; Qing,Guo ^[5] ; Li-Jun,Liang ^[6]

作者单位： Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.;School of Public Health, Sun Yat-Sen University, Guangzhou, 510080, China.;Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Center for Disease Control and Prevention, Guangzhou, 511430, China. ^[1] Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Center for Disease Control and Prevention, Guangzhou, 511430, China.;School of Public Health, Southern Medical University, Guangzhou, 510515, China.;School of Public Health, Southwest Medical University, Luzhou, 646000, China. ^[2] School of Public Health, Sun Yat-Sen University, Guangzhou, 510080, China. pphuang1@163.com.;Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Center for Disease Control and Prevention, Guangzhou, 511430, China. pphuang1@163.com.;Guangdong Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Center for Disease Control and Prevention, Guangzhou, 511430, China. pphuang1@163.com.;School of Public Health, Southern Medical University, Guangzhou, 510515, China. pphuang1@163.com. ^[3] Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Center for Disease Control and Prevention, Guangzhou, 511430, China.;Guangdong Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Center for Disease Control and Prevention, Guangzhou, 511430, China.;School of Public Health, Southern Medical University, Guangzhou, 510515, China. ^[4] Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. ^[5] Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Center for Disease Control and Prevention, Guangzhou, 511430, China.;Guangdong Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Center for Disease Control and Prevention, Guangzhou, 511430, China. ^[6]

关键词 Charged amino acid Evolution Influenza Outbreak Single nucleotide variant (SNV)Statistics