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Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates.

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第一作者: Matthew,Gagne
第一单位: Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
作者单位: Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. [1] Department of Pediatrics, Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.;Emory Vaccine Center, Emory University, Atlanta, GA, USA.;Emory National Primate Research Center, Atlanta, GA, USA. [2] Bioqual, Inc., Rockville, MD, USA. [3] Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. [4] Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA. [5] Biostatistics Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. [6] Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.;Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.;Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.;The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA.;Center for Vaccines & Immunity to Microbial Pathogens, Washington University School of Medicine, St. Louis, MO, USA. [7] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. ddouek@mail.nih.gov. [8] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. rseder@mail.nih.gov. [9]
DOI 10.1038/s41590-024-01951-5
PMID 39227514
发布时间 2025-01-17
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