首页> BMC medicine> A functional variant rs912304 for late-onset T1D risk contributes to islet dysfunction by regulating proinflammatory cytokine-responsive gene STXBP6 expression.

A functional variant rs912304 for late-onset T1D risk contributes to islet dysfunction by regulating proinflammatory cytokine-responsive gene STXBP6 expression.

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第一作者： Yu,Qian

第一单位： Department of Endocrinology and Metabolism, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.

作者： Yu,Qian ^[1] ; Shu,Chen ^[2] ; Yan,Wang ^[1] ; Yuyue,Zhang ^[1] ; Jie,Zhang ^[1] ; Liying,Jiang ^[1] ; Hao,Dai ^[1] ; Min,Shen ^[1] ; Yunqiang,He ^[1] ; Hemin,Jiang ^[1] ; Tao,Yang ^[1] ; Qi,Fu ^[3] ; Kuanfeng,Xu ^[4]

作者单位： Department of Endocrinology and Metabolism, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. ^[1] Department of Endocrinology and Metabolism, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.;Department of Endocrinology, Affiliated Hospital 2 of Nantong University, Nantong First People's Hospital, Nantong, 226000, China. ^[2] Department of Endocrinology and Metabolism, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. drfuqi@njmu.edu.cn. ^[3] Department of Endocrinology and Metabolism, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. kuanfengxu@njmu.edu.cn. ^[4]

关键词 Islet autoimmunity Islet function Stxbp6 T1D Variant