Local delivery of platelet-derived factors mitigates ischemia and preserves ovarian function through angiogenic modulation: A personalized regenerative strategy for fertility preservation.

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作者： Nanum,Chung ^[1] ; Chungmo,Yang ^[2] ; Heeseon,Yang ^[1] ; Jungwoo,Shin ^[1] ; Chae Young,Song ^[1] ; Hyewon,Min ^[1] ; Ji Hyang,Kim ^[3] ; Kangwon,Lee ^[4] ; Jung Ryeol,Lee ^[5]

作者单位： Department of Translational Medicines, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea; Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea. ^[1] Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea; Program in Nanoscience and Technology, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, Republic of Korea. ^[2] Department of Obstetrics and Gynecology, Fertility Center of CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, 13496, Republic of Korea. Electronic address: bin0902@chamc.co.kr. ^[3] Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, Republic of Korea. Electronic address: kangwonlee@snu.ac.kr. ^[4] Department of Translational Medicines, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea; Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. Electronic address: leejrmd@snu.ac.kr. ^[5]

关键词 Avascular transplantation Fertility preservation Fibrin Ischemia Neovascularization Personalized regenerative medicine Platelet-rich plasma