MEF2A, a gene associated with mitochondrial biogenesis, promotes drug resistance in gastric cancer.

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作者： Yao,Shen ^[1] ; Tong,Zhang ^[1] ; Xueyuan,Jia ^[1] ; Fei,Xi ^[1] ; Wanting,Jing ^[1] ; Yusi,Wang ^[1] ; Min,Huang ^[1] ; Ruisi,Na ^[2] ; Lidan,Xu ^[1] ; Wei,Ji ^[1] ; Yuandong,Qiao ^[1] ; Xuelong,Zhang ^[1] ; Wenjing,Sun ^[1] ; Shuijie,Li ^[3] ; Jie,Wu ^[4]

作者单位： Laboratory of Medical Genetics, Harbin Medical University, Harbin, China; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, China. ^[1] Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China. ^[2] State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Biopharmaceutical Sciences, College of Pharmacy, Harbin Medical University, Harbin, China. Electronic address: shuijie.li@hrbmu.edu.cn. ^[3] Laboratory of Medical Genetics, Harbin Medical University, Harbin, China; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, China; Future Medical Laboratory, the 2nd Affiliated Hospital of Harbin Medical University, Harbin, China. Electronic address: wujie@hrbmu.edu.cn. ^[4]

关键词 Drug resistance GC MEF2A Mitochondria PGC1α

主题词胃肿瘤(Stomach Neoplasms);人类(Humans);抗药性, 肿瘤(Drug Resistance, Neoplasm);顺铂(Cisplatin);细胞系, 肿瘤(Cell Line, Tumor);动物(Animals);小鼠(Mice);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);NF-E2相关因子2(NF-E2-Related Factor 2);男(雄)性(Male);线粒体(Mitochondria);信号传导(Signal Transduction);小鼠, 裸(Mice, Nude);女(雌)性(Female);抗肿瘤药(Antineoplastic Agents);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1016/j.bbadis.2024.167497

PMID 39237047

发布时间 2024-11-26

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Biochimica et biophysica acta. Molecular basis of disease

2025年1871卷1期

167497页

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MEF2A, a gene associated with mitochondrial biogenesis, promotes drug resistance in gastric cancer.

Biochimica et biophysica acta. Molecular basis of disease

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Biochimica et biophysica acta. Molecular basis of disease

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MEF2A, a gene associated with mitochondrial biogenesis, promotes drug resistance in gastric cancer.

Biochimica et biophysica acta. Molecular basis of disease

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Biochimica et biophysica acta. Molecular basis of disease

相关期刊

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