首页> Nature communications> Targeting PRMT3 impairs methylation and oligomerization of HSP60 to boost anti-tumor immunity by activating cGAS/STING signaling.

Targeting PRMT3 impairs methylation and oligomerization of HSP60 to boost anti-tumor immunity by activating cGAS/STING signaling.

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第一作者： Yunxing,Shi

第一单位： State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China.;Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, China.;Department of Colorectal Surgery, Guangdong Institute of Gastroenterology, and Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

作者： Yunxing,Shi ^[1] ; Zongfeng,Wu ^[2] ; Shaoru,Liu ^[2] ; Dinglan,Zuo ^[2] ; Yi,Niu ^[2] ; Yuxiong,Qiu ^[2] ; Liang,Qiao ^[2] ; Wei,He ^[2] ; Jiliang,Qiu ^[2] ; Yunfei,Yuan ^[3] ; Guocan,Wang ^[4] ; Binkui,Li ^[5]

作者单位： State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China.;Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, China.;Department of Colorectal Surgery, Guangdong Institute of Gastroenterology, and Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. ^[1] State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China.;Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, China. ^[2] State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China. yuanyf@mail.sysu.edu.cn.;Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, China. yuanyf@mail.sysu.edu.cn. ^[3] Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. gwang6@mdanderson.org. ^[4] State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China. libk@sysucc.org.cn.;Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, China. libk@sysucc.org.cn. ^[5]