换一批HIV-TAT dysregulates microglial lipid metabolism through SREBP2/miR-124 axis: Implication of lipid droplet accumulation microglia in NeuroHIV.
第一作者：
Yan,Cheng
第一单位：
Department of Biomedical and Translational Sciences, Macro & Joan Brock Virginia Health Sciences at Old Dominion University, Norfolk, VA 23507, USA.
作者：
医学主题词
动物(Animals);小神经胶质细胞(Microglia);微RNAs(MicroRNAs);胆固醇调节元件结合蛋白质2(Sterol Regulatory Element Binding Protein 2);脂类代谢(Lipid Metabolism);小鼠(Mice);tat基因产物, 人免疫缺陷病毒(tat Gene Products, Human Immunodeficiency Virus);胆固醇(Cholesterol);脑(Brain);HIV感染(HIV Infections);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);艾滋病痴呆复合征(AIDS Dementia Complex);炎性体(Inflammasomes)
DOI
10.1016/j.bbi.2024.09.011
PMID
39260763
发布时间
2026-01-02
基金项目
R01 DA054826/DA/NIDA NIH HHS/United States
R21 DA042704/DA/NIDA NIH HHS/United States
R34 DA061156/DA/NIDA NIH HHS/United States
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Brain, behavior, and immunity
108-122页
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