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MultiSCRIPT-Cycle 1-a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial.

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第一作者: Perrine,Janiaud
第一单位: Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.
作者单位: Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland. [1] Neurology Clinic Lugano, Neurocenter of Southern Switzerland, Lugano, MS Center, Switzerland.;Faculty of Biomedical Sciences, Università Della Svizzera Italiana (USI), Lugano, Switzerland. [2] Department of Neurology, Ruhr-University Bochum, St. Josef-Hospital, Bochum, Germany. [3] Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland. [4] Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.;MS Centre, Neurologic Clinic and Policlinic, University Hospital Basel, Basel, Switzerland. [5] Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.;Department of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland. [6] Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.;MS Centre, Neurologic Clinic and Policlinic, University Hospital Basel, Basel, Switzerland.;Department of Medicine and Biomedical Engineering, Translational Imaging in Neurology Basel, University Hospital Basel, University of Basel, Basel, Switzerland. [7] Department of Neurology, Cantonal Hospital Aarau, Aarau, Switzerland. [8] Department of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland. [9] Division of Neurology, Department of Clinical Neurosciences, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland. [10] Department of Neurology, Cantonal Hospital St, Gallen, St. Gallen, Switzerland. [11] Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV) and, University of Lausanne, Lausanne, Switzerland. [12] Department of Neurology, Bern University Hospital and University of Bern, Bern, Switzerland. [13] Neurology Clinic Lugano, Neurocenter of Southern Switzerland, Lugano, MS Center, Switzerland. [14] Bristol Population Health Science Institute, University of Bristol, Bristol, UK. [15] Health Economics Facility, Department of Public Health, University of Basel, Basel, Switzerland.;Institute of Pharmaceutical Medicine (ECPM), University of Basel, Basel, Switzerland. [16] Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.;Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.;MS Centre, Neurologic Clinic and Policlinic, University Hospital Basel, Basel, Switzerland.;Department of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland. [17] Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.;Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.;MS Centre, Neurologic Clinic and Policlinic, University Hospital Basel, Basel, Switzerland.;Department of Medicine and Biomedical Engineering, Translational Imaging in Neurology Basel, University Hospital Basel, University of Basel, Basel, Switzerland. [18] Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland. lars.hemkens@usb.ch.;Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland. lars.hemkens@usb.ch. [19]
DOI 10.1186/s13063-024-08454-6
PMID 39261900
发布时间 2025-01-30
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