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Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis.

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作者: Xinran,Li [1] ; Xiao,Li [2] ; Cong,Xiang [2] ; Jin,Cao [3] ; Jiansheng,Guo [4] ; Shilei,Zhu [3] ; Jingyi,Tan [2] ; Lijing,Wang [2] ; Chun,Gao [2] ; Shengduo,Liu [2] ; Lifeng,Zhao [5] ; Bo,Yuan [3] ; Pinglong,Xu [6] ; Bing,Yang [2] ; Dali,Li [7] ; Bin,Zhao [3] ; Xin-Hua,Feng [8]
作者单位: MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Molecular Cancer Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China; ZJU-Hangzhou Global Scientific and Technological Innovation Center, Hangzhou, Zhejiang 311200, China; Center for Life Sciences, Shaoxing Institute, Zhejiang University, Shaoxing, Zhejiang 321000, China; Cancer Center, Zhejiang University, Hangzhou, Zhejiang 310058, China. [1] MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Molecular Cancer Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China. [2] MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Molecular Cancer Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China; Center for Life Sciences, Shaoxing Institute, Zhejiang University, Shaoxing, Zhejiang 321000, China; Cancer Center, Zhejiang University, Hangzhou, Zhejiang 310058, China. [3] Center of Cryo-Electron Microscopy, Zhejiang University, Hangzhou, Zhejiang 310058, China. [4] ZJU-Hangzhou Global Scientific and Technological Innovation Center, Hangzhou, Zhejiang 311200, China. [5] MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Molecular Cancer Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China; ZJU-Hangzhou Global Scientific and Technological Innovation Center, Hangzhou, Zhejiang 311200, China; Cancer Center, Zhejiang University, Hangzhou, Zhejiang 310058, China. [6] Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China. [7] MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Molecular Cancer Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China; Center for Life Sciences, Shaoxing Institute, Zhejiang University, Shaoxing, Zhejiang 321000, China; Cancer Center, Zhejiang University, Hangzhou, Zhejiang 310058, China; The Second Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang 310009, China. Electronic address: fenglab@zju.edu.cn. [8]
DOI 10.1016/j.celrep.2024.114728
PMID 39264808
发布时间 2025-01-22
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