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DOR activation in mature oligodendrocytes regulates α-ketoglutarate metabolism leading to enhanced remyelination in aged mice.

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第一作者: Guojiao,Huang
第一单位: Center for Translational Medicine, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, China.
作者: Guojiao,Huang [1] ; Zhidan,Li [1] ; Xuezhao,Liu [2] ; Menglong,Guan [1] ; Songlin,Zhou [3] ; Xiaowen,Zhong [2] ; Tao,Zheng [1] ; Dazhuan,Xin [2] ; Xiaosong,Gu [3] ; Dezhi,Mu [1] ; Yingkun,Guo [1] ; Lin,Zhang [1] ; Liguo,Zhang [4] ; Q Richard,Lu [2] ; Xuelian,He [5]
作者单位: Center for Translational Medicine, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, China. [1] Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. [2] Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, China. [3] Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China. [4] Center for Translational Medicine, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, China. Xuelian_he2021@scu.edu.cn. [5]
DOI 10.1038/s41593-024-01754-9
PMID 39266660
发布时间 2024-12-05
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