Five-year outcomes with first-line nivolumab plus ipilimumab with 2 cycles of chemotherapy versus 4 cycles of chemotherapy alone in patients with metastatic non-small cell lung cancer in the randomized CheckMate 9LA trial.

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第一作者： Martin,Reck

第一单位： Airway Research Center North, German Center for Lung Research, LungClinic, Grosshansdorf, Germany. Electronic address: m.reck@lungenclinic.de.

作者： Martin,Reck ^[1] ; Tudor-Eliade,Ciuleanu ^[2] ; Michael,Schenker ^[3] ; Stephanie,Bordenave ^[4] ; Manuel,Cobo ^[5] ; Oscar,Juan-Vidal ^[6] ; Niels,Reinmuth ^[7] ; Eduardo,Richardet ^[8] ; Enriqueta,Felip ^[9] ; Juliana,Menezes ^[10] ; Ying,Cheng ^[11] ; Hideaki,Mizutani ^[12] ; Bogdan,Zurawski ^[13] ; Aurelia,Alexandru ^[14] ; David P,Carbone ^[15] ; Shun,Lu ^[16] ; Thomas,John ^[17] ; Takekazu,Aoyama ^[18] ; Diederik J,Grootendorst ^[18] ; Nan,Hu ^[18] ; Laura J,Eccles ^[18] ; Luis G,Paz-Ares ^[19]

作者单位： Airway Research Center North, German Center for Lung Research, LungClinic, Grosshansdorf, Germany. Electronic address: m.reck@lungenclinic.de. ^[1] Institutul Oncologic Prof Dr Ion Chiricuţă and University of Medicine and Pharmacy Iuliu Haţieganu, Cluj-Napoca, Romania. ^[2] SF Nectarie Oncology Center, Craiova, Romania. ^[3] L'institut du Thorax, Nantes, France. ^[4] Unidad de Gestión Clínica Intercentros de Oncología Médica, Hospitales Universitarios Regional y Virgen de la Victoria, IBIMA, Málaga, Spain. ^[5] Hospital Universitario La Fe, Valencia, Spain. ^[6] Asklepios Lung Clinic, member of the German Center for Lung Research, Munich-Gauting, Germany. ^[7] IONC Instituto Oncológico de Córdoba, Cordoba, Argentina. ^[8] Medical Oncology Service, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. ^[9] Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil. ^[10] Jilin Cancer Hospital, Changchun, Jilin, China. ^[11] Saitama Cancer Center, Saitama, Japan. ^[12] Chemotherapy Department, Ambulatorium Chemioterapii, Bydgoszcz, Poland. ^[13] Department of Oncology, Institute of Oncology Prof Dr Alexandru Trestioreanu Bucha, Bucharest, Romania. ^[14] The Ohio State University Comprehensive Cancer Center and the Pelotonia Institute for Immuno-Oncology, Columbus, OH, United States. ^[15] Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China. ^[16] Austin Hospital, Heidelberg, Victoria, Australia. ^[17] Bristol Myers Squibb, Princeton, NJ, United States. ^[18] Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain. ^[19]

关键词 Cancer Chemotherapy drug Immunotherapy Ipilimumab Nivolumab Non-small-cell lung carcinoma