首页> Molecular cancer> Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1 + antiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomics.

Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1 + antiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomics.

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第一作者： Sophie,Cousin

第一单位： Department of Medicine, Institut Bergonié, 229 cours de l'Argonne, Bordeaux, 33000, France.

作者： Sophie,Cousin ^[1] ; Jean-Philippe,Guégan ^[2] ; Kohei,Shitara ^[3] ; Lola Jade,Palmieri ^[4] ; Jean Philippe,Metges ^[5] ; Simon,Pernot ^[1] ; Shota,Fukuoka ^[6] ; Shohei,Koyama ^[6] ; Hiroyoshi,Nishikawa ^[6] ; Carine A,Bellera ^[7] ; Antoine,Adenis ^[8] ; Carlos A,Gomez-Roca ^[9] ; Philippe Alexandre,Cassier ^[10] ; Antoine,Hollebecque ^[11] ; Coralie,Cantarel ^[7] ; Michèle,Kind ^[12] ; Isabelle,Soubeyran ^[13] ; Lucile,Vanhersecke ^[13] ; Alban,Bessede ^[2] ; Antoine,Italiano ^[14]

作者单位： Department of Medicine, Institut Bergonié, 229 cours de l'Argonne, Bordeaux, 33000, France. ^[1] Explicyte, Bordeaux, France. ^[2] Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, 277-8577, Japan. ^[3] Department of Medicine, Institut Bergonié, 229 cours de l'Argonne, Bordeaux, 33000, France.;Explicyte, Bordeaux, France. ^[4] Department of Oncology, University Hospital Center of Brest, Brest, France. ^[5] Division of Cancer Immunology, Research Institute/Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, Tokyo, Chiba, 104-0045, 277-8577, Japan. ^[6] Bordeaux Population Health Research Center, Univ. Bordeaux, Epicene team, UMR 1219, Inserm, Bordeaux, France.;Clinical and Epidemiological Research Unit, INSERM CIC1401, Bordeaux, France. ^[7] Department of Medicine, Institut Cancerologie Montpellier, Montpellier, France. ^[8] Department of Medicine, Oncopole, Toulouse, France. ^[9] Department of Medicine, Centre Leon Bérard, Lyon, France. ^[10] DITEP, Gustave Roussy, Villejuif, France. ^[11] Department of Radiology, Institut Bergonié, Bordeaux, France. ^[12] Department of Pathology, Institut Bertognié, Bordeaux, France. ^[13] Department of Medicine, Institut Bergonié, 229 cours de l'Argonne, Bordeaux, 33000, France. a.italiano@bordeaux.unicancer.fr.;Department of Medicine, Centre Leon Bérard, Lyon, France. a.italiano@bordeaux.unicancer.fr.;Faculty of Medicine, University of Bordeaux, Bordeaux, France. a.italiano@bordeaux.unicancer.fr. ^[14]