换一批Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization.
第一作者：
Sara M,Willems
第一单位：
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.;General Medicine Center, Saarland University Faculty of Medicine, Homburg, 66421, Germany.
作者：
Sara M,Willems [1]
;
Natasha H J,Ng [2]
;
Juan,Fernandez [3]
;
Rebecca S,Fine [4]
;
Eleanor,Wheeler [5]
;
Jennifer,Wessel [6]
;
Hidetoshi,Kitajima [3]
;
Gaelle,Marenne [7]
;
Xueling,Sim [8]
;
Hanieh,Yaghootkar [9]
;
Shuai,Wang [10]
;
Sai,Chen [11]
;
Yuning,Chen [10]
;
Yii-Der Ida,Chen [12]
;
Niels,Grarup [13]
;
Ruifang,Li-Gao [14]
;
Tibor V,Varga [15]
;
Jennifer L,Asimit [16]
;
Shuang,Feng [17]
;
Rona J,Strawbridge [18]
;
Erica L,Kleinbrink [19]
;
Tarunveer S,Ahluwalia [20]
;
Ping,An [21]
;
Emil V,Appel [13]
;
Dan E,Arking [22]
;
Juha,Auvinen [23]
;
Lawrence F,Bielak [24]
;
Nathan A,Bihlmeyer [25]
;
Jette,Bork-Jensen [13]
;
Jennifer A,Brody [26]
;
Archie,Campbell [27]
;
Audrey Y,Chu [28]
;
Gail,Davies [29]
;
Ayse,Demirkan [30]
;
James S,Floyd [26]
;
Franco,Giulianini [28]
;
Xiuqing,Guo [12]
;
Stefan,Gustafsson [31]
;
Anne U,Jackson [11]
;
Johanna,Jakobsdottir [32]
;
Marjo-Riitta,Järvelin [33]
;
Richard A,Jensen [26]
;
Stavroula,Kanoni [34]
;
Sirkka,Keinanen-Kiukaanniemi [35]
;
Man,Li [36]
;
Yingchang,Lu [37]
;
Jian'an,Luan [38]
;
Alisa K,Manning [39]
;
Jonathan,Marten [40]
;
Karina,Meidtner [41]
;
Dennis O,Mook-Kanamori [42]
;
Taulant,Muka [43]
;
Giorgio,Pistis [44]
;
Bram,Prins [7]
;
Kenneth M,Rice [45]
;
Serena,Sanna [46]
;
Albert Vernon,Smith [47]
;
Jennifer A,Smith [48]
;
Lorraine,Southam [49]
;
Heather M,Stringham [11]
;
Vinicius,Tragante [50]
;
Sander W,van der Laan [51]
;
Helen R,Warren [52]
;
Jie,Yao [12]
;
Andrianos M,Yiorkas [53]
;
Weihua,Zhang [54]
;
Wei,Zhao [24]
;
Mariaelisa,Graff [55]
;
Heather M,Highland [56]
;
Anne E,Justice [55]
;
Eirini,Marouli [34]
;
Carolina,Medina-Gomez [57]
;
Saima,Afaq [58]
;
Wesam A,Alhejily [59]
;
Najaf,Amin [30]
;
Folkert W,Asselbergs [60]
;
Lori L,Bonnycastle [61]
;
Michiel L,Bots [62]
;
Ivan,Brandslund [63]
;
Ji,Chen [7]
;
John,Danesh [64]
;
Renée,de Mutsert [14]
;
Abbas,Dehghan [65]
;
Tapani,Ebeling [66]
;
Paul,Elliott [67]
;
EPIC-Interact Consortium [68]
;
Aliki-Eleni,Farmaki [69]
;
Jessica D,Faul [70]
;
Paul W,Franks [71]
;
Steve,Franks [72]
;
Andreas,Fritsche [13]
;
Anette P,Gjesing [73]
;
Mark O,Goodarzi [47]
;
Vilmundur,Gudnason [74]
;
Göran,Hallmans [32]
;
Tamara B,Harris [75]
;
Karl-Heinz,Herzig [76]
;
Marie-France,Hivert [77]
;
Torben,Jørgensen [78]
;
Marit E,Jørgensen [79]
;
Pekka,Jousilahti [80]
;
Eero,Kajantie [81]
;
Maria,Karaleftheri [24]
;
Sharon L R,Kardia [79]
;
Leena,Kinnunen [82]
;
Heikki A,Koistinen [83]
;
Pirjo,Komulainen [84]
;
Peter,Kovacs [85]
;
Johanna,Kuusisto [85]
;
Markku,Laakso [86]
;
Leslie A,Lange [87]
;
Lenore J,Launer [88]
;
Aaron,Leong [79]
;
Jaana,Lindström [89]
;
Jocelyn E,Manning Fox [79]
;
Satu,Männistö [90]
;
Nisa M,Maruthur [91]
;
Leena,Moilanen [92]
;
Antonella,Mulas [93]
;
Mike A,Nalls [94]
;
Matthew,Neville [95]
;
James S,Pankow [96]
;
Alison,Pattie [97]
;
Eva R B,Petersen [98]
;
Hannu,Puolijoki [99]
;
Asif,Rasheed [96]
;
Paul,Redmond [100]
;
Frida,Renström [101]
;
Michael,Roden [102]
;
Danish,Saleheen [103]
;
Juha,Saltevo [104]
;
Kai,Savonen [105]
;
Sylvain,Sebert [106]
;
Tea,Skaaby [107]
;
Kerrin S,Small [85]
;
Alena,Stančáková [108]
;
Jakob,Stokholm [109]
;
Konstantin,Strauch [110]
;
E-Shyong,Tai [12]
;
Kent D,Taylor [106]
;
Betina H,Thuesen [111]
;
Anke,Tönjes [112]
;
Emmanouil,Tsafantakis [113]
;
Tiinamaija,Tuomi [114]
;
Jaakko,Tuomilehto [115]
;
Understanding Society Scientific Group [116]
;
Matti,Uusitupa [62]
;
Marja,Vääräsmäki [117]
;
Ilonca,Vaartjes [118]
;
Magdalena,Zoledziewska [119]
;
Goncalo,Abecasis [108]
;
Beverley,Balkau [53]
;
Hans,Bisgaard [120]
;
Alexandra I,Blakemore [121]
;
Matthias,Blüher [122]
;
Heiner,Boeing [108]
;
Eric,Boerwinkle [123]
;
Klaus,Bønnelykke [52]
;
Erwin P,Bottinger [124]
;
Mark J,Caulfield [125]
;
John C,Chambers [126]
;
Daniel I,Chasman [61]
;
Ching-Yu,Cheng [127]
;
Francis S,Collins [92]
;
Josef,Coresh [128]
;
Francesco,Cucca [29]
;
Gert J,de Borst [129]
;
Ian J,Deary [130]
;
George,Dedoussis [131]
;
Panos,Deloukas [132]
;
Hester M,den Ruijter [87]
;
Josée,Dupuis [133]
;
Michele K,Evans [43]
;
Ele,Ferrannini [134]
;
Oscar H,Franco [135]
;
Harald,Grallert [136]
;
Torben,Hansen [40]
;
Andrew T,Hattersley [137]
;
Caroline,Hayward [30]
;
Joel N,Hirschhorn [138]
;
Arfan,Ikram [139]
;
Erik,Ingelsson [140]
;
Fredrik,Karpe [141]
;
Kay-Tee,Kaw [142]
;
Wieland,Kiess [141]
;
Jaspal S,Kooner [143]
;
Antje,Körner [38]
;
Timo,Lakka [144]
;
Claudia,Langenberg [145]
;
Lars,Lind [146]
;
Cecilia M,Lindgren [147]
;
Allan,Linneberg [10]
;
Leonard,Lipovich [30]
;
Ching-Ti,Liu [148]
;
Jun,Liu [149]
;
Yongmei,Liu [89]
;
Ruth J F,Loos [150]
;
Patrick E,MacDonald [151]
;
Karen L,Mohlke [52]
;
Andrew D,Morris [152]
;
Patricia B,Munroe [153]
;
Alison,Murray [154]
;
Sandosh,Padmanabhan [155]
;
Colin N A,Palmer [13]
;
Gerard,Pasterkamp [24]
;
Oluf,Pedersen [156]
;
Patricia A,Peyser [27]
;
Ozren,Polasek [21]
;
David,Porteous [157]
;
Michael A,Province [83]
;
Bruce M,Psaty [158]
;
Rainer,Rauramaa [159]
;
Paul M,Ridker [139]
;
Olov,Rolandsson [14]
;
Patrik,Rorsman [151]
;
Frits R,Rosendaal [79]
;
Igor,Rudan [41]
;
Veikko,Salomaa [160]
;
Matthias B,Schulze [154]
;
Robert,Sladek [107]
;
Blair H,Smith [161]
;
Timothy D,Spector [111]
;
John M,Starr [30]
;
Michael,Stumvoll [162]
;
Cornelia M,van Duijn [38]
;
Mark,Walker [69]
;
Nick J,Wareham [163]
;
David R,Weir [126]
;
James G,Wilson [164]
;
Tien Yin,Wong [87]
;
Eleftheria,Zeggini [12]
;
Alan B,Zonderman [165]
;
Jerome I,Rotter [11]
;
Andrew P,Morris [166]
;
Michael,Boehnke [167]
;
Jose C,Florez [168]
;
Mark I,McCarthy [169]
;
James B,Meigs [38]
;
Anubha,Mahajan [170]
;
Robert A,Scott [171]
;
Anna L,Gloyn ;
Inês,Barroso
作者单位：
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.;General Medicine Center, Saarland University Faculty of Medicine, Homburg, 66421, Germany.
[1]
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OX3 7LE, UK.;Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.
[2]
Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
[3]
Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.;Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, 02115, USA.;Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.;Current address: Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA, 02210, USA.
[4]
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.;Department of Human Genetics, Wellcome Sanger Institute, Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
[5]
Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.;Departments of Epidemiology & Medicine, Schools of Public Health & Medicine, Indiana University, Indianapolis, IN, 46202, USA.;Diabetes Translational Research Center, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.;General Medicine Division, Massachusetts General Hospital, Boston, MA, USA.
[6]
Department of Human Genetics, Wellcome Sanger Institute, Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
[7]
Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore, 117549, Singapore.;Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA.
[8]
Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK.
[9]
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
[10]
Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA.
[11]
The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.
[12]
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark.
[13]
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.
[14]
Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, SE-205 02, Sweden.
[15]
Department of Human Genetics, Wellcome Sanger Institute, Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.;MRC Biostatistics Unit, University of Cambridge, Cambridge, CB2 0SR, UK.
[16]
Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
[17]
Mental Health and Wellbeing, School of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8RZ, UK.;Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institute, Stockholm, 171 76, Sweden.
[18]
Quantitative Life Sciences, McGill University, Montreal, Quebec, Canada.;Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, 48201-1928, USA.
[19]
COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.;Steno Diabetes Center Copenhagen, Gentofte, 2820, Denmark.
[20]
Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, 63108, USA.
[21]
McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
[22]
Center for Life Course Health Research, University of Oulu, Oulu, 90014, Finland.;Unit of Primary Care, Oulu University Hospital, Oulu, Finland.
[23]
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA.
[24]
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
[25]
Cardiovascular Health Research Unit, University of Washington, Seattle, WA, 98195, USA.;Department of Medicine, University of Washington, Seattle, WA, USA.
[26]
Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.
[27]
Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.
[28]
Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.;Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.
[29]
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 GE, The Netherlands.
[30]
Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, 75237, Sweden.
[31]
Icelandic Heart Association, Kopavogur, Iceland.
[32]
Center for Life Course Health Research, University of Oulu, Oulu, 90014, Finland.;Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, W2 1PG, UK.;Biocenter Oulu, University of Oulu, Oulu, Finland.
[33]
William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
[34]
Faculty of Medicine, Center for Life Course Health Research, University of Oulu, Oulu, Finland.;MRC and Unit of Primary Care, Oulu University Hospital, Oulu, Finland.
[35]
Division of Nephrology, Internal Medicine, School of Medicine, University of Utah, Salt Lake City, USA.;Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
[36]
The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, 10069, USA.;Department of Medicine, Division of Genetic Medicine, Vanderbilt Genetics Institute, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA.
[37]
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
[38]
Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA, 02114, USA.;Department of Medicine, Harvard Medical School, Boston, MA, USA.
[39]
Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.
[40]
Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, 14558, Germany.;German Center for Diabetes Research (DZD), München-Neuherberg, 85764, Germany.
[41]
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.;Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.
[42]
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 GE, The Netherlands.;Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
[43]
Italian National Research Council, Institute of Genetics and Biomedic Research, Cittadella Universitaria, Monserrato, 09042, Italy.;Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA.
[44]
Cardiovascular Health Research Unit, University of Washington, Seattle, WA, 98195, USA.;Department of Biostatistics, University of Washington, Seattle, WA, USA.
[45]
Italian National Research Council, Institute of Genetics and Biomedic Research, Cittadella Universitaria, Monserrato, 09042, Italy.;University Medical Center Groningen, Department of Genetics, University of Groningen, Groningen, 9700 RB, The Netherlands.
[46]
Icelandic Heart Association, Kopavogur, Iceland.;Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
[47]
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA.;Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA.
[48]
Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.;Department of Human Genetics, Wellcome Sanger Institute, Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.;Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
[49]
Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, 3584CX, The Netherlands.
[50]
Central Diagnostics Laboratory, Division Laboratories, Pharmacy, and Biomedical genetics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
[51]
William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.;Barts Cardiovascular Research Unit, Barts and The London School of Medicine & Dentistry, Queen Mary University, London, EC1M 6BQ, UK.
[52]
Section of Investigative Medicine, Department of Medicine, Imperial College London, London, W12 0NN, UK.;Department of Life Sciences, Brunel University London, London, UB8 3PH, UK.
[53]
Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.;Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UB1 3HW, UK.
[54]
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27514, USA.
[55]
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27514, USA.;Human Genetics Center, The University of Texas School of Public Health; The University of Texas Graduate School of Biomedical Sciences at Houston;, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
[56]
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 GE, The Netherlands.;Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, 3015 GE, The Netherlands.
[57]
Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, W2 1PG, UK.
[58]
William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.;Department of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
[59]
Amsterdam University Medical Centers, Department of Cardiology, University of Amsterdam, Amsterdam, The Netherlands.;Health Data Research UK and Institute of Health Informatics, University College London, London, UK.
[60]
Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD, 20892, USA.
[61]
Center for Circulatory Health, University Medical Center Utrecht, Utrecht, 3508GA, The Netherlands.
[62]
Department of Clinical Biochemistry, Lillebaelt Hospital Vejle, Vejle, 7100, Denmark.;Institute of Regional Health Research, University of Southern Denmark, Odense, 5000, Denmark.
[63]
Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB18RN, UK.
[64]
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 GE, The Netherlands.;Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, W2 1PG, UK.;UK Dementia Research Institute, Imperial College London, London, UK.
[65]
Oulu University Hospital, Oulu, 90220, Finland.
[66]
Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, W2 1PG, UK.;Imperial College NIHR Biomedical Research Centre, London, UK.;Health Data Research UK, Imperial College London, London, UK.
[67]
Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, 17671, Greece.;Department of Population Science and Experimental Medicine, Institute of Cardiovascular Science, University College London, London, UK.
[68]
Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA.
[69]
Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, 02115, USA.;Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, SE-205 02, Sweden.;Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.
[70]
Institute of Reproductive and Developmental Biology, Imperial College London, London, W12 0NN, UK.
[71]
German Center for Diabetes Research (DZD), München-Neuherberg, 85764, Germany.;Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology, and Clinical Chemistry, University Hospital of Tübingen, Tübingen, Germany.
[72]
Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
[73]
Department of Biobank Research, Umeå University, Umeå, SE-901 87, Sweden.
[74]
Institute of Biomedicine and Biocenter of Oulu, Faculty of Medicine, Medical Research Center Oulu and Oulu University Hospital, Oulu, Finland.;Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan, 60-572, Poland.
[75]
Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, USA.;Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
[76]
Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, 2000, Denmark.;Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark.;Faculty of Medicine, University of Aalborg, Aalborg, 9100, Denmark.
[77]
Steno Diabetes Center Copenhagen, Gentofte, 2820, Denmark.;National Institute of Public Health, Southern Denmark University, Odense, 5000, Denmark.
[78]
Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, FI-00271, Finland.
[79]
Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, FI-00271, Finland.;PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.;Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.;Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
[80]
Echinos Medical Centre, Echinos, Greece.
[81]
Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, FI-00271, Finland.;University of Helsinki and Department of Medicine, Helsinki University Hospital, Helsinki, FI-00029, Finland.;Minerva Foundation Institute for Medical Research, Biomedicum 2U Helsinki, Helsinki, FI-00290, Finland.
[82]
Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland.
[83]
Integrated Research and Treatment (IFB) Center Adiposity Diseases, University of Leipzig, Leipzig, 04103, Germany.;Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, 04103, Germany.
[84]
Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland.
[85]
Department of Medicine, Division of Bioinformatics and Personalized Medicine, University of Colorado Denver, Denver, CO, USA.
[86]
Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
[87]
Division of General Internal Medicine, Massachusetts General Hospital, Department of Medicine, Harvard Medical School, Boston, MA, USA.
[88]
Alberta Diabetes Institute IsletCore, University of Alberta, Edmonton, T6G 2E1, Canada.;Department of Pharmacology, University of Alberta, Edmonton, T6G 2E1, Canada.
[89]
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.;Department of Medicine, Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.;Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, MD, USA.
[90]
Kuopio University Hospital, Kuopio, 70210, Finland.
[91]
Italian National Research Council, Institute of Genetics and Biomedic Research, Cittadella Universitaria, Monserrato, 09042, Italy.;Dipartimento di Scienze Biomediche, Università degli Studi di Sassari, Sassari, 07100, Italy.
[92]
Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, 20892, USA.;Data Tecnica International LLC, Glen Echo, MD, 20812, USA.
[93]
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OX3 7LE, UK.
[94]
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, 55455, USA.
[95]
Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.
[96]
Department of Clinical Biochemistry, Lillebaelt Hospital Vejle, Vejle, 7100, Denmark.
[97]
South Ostobothnia Central Hospital, Seinajoki, 60220, Finland.
[98]
Center for Non-Communicable Diseases, Karachi, Pakistan.
[99]
Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, SE-205 02, Sweden.;Department of Biobank Research, Umeå University, Umeå, SE-901 87, Sweden.
[100]
German Center for Diabetes Research (DZD), München-Neuherberg, 85764, Germany.;Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.;Division of Endocrinology and Diabetology, Medical Faculty, University Hospital Düsseldorf, Düsseldorf, Germany.
[101]
Center for Non-Communicable Diseases, Karachi, Pakistan.;Department of Biostatistics and Epidemiology, University of Pennsylvania, 19104, USA.
[102]
Central Finland Central Hospital, Jyvaskyla, 40620, Finland.
[103]
Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland.;Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, 70029, Finland.
[104]
Biocenter Oulu, University of Oulu, Oulu, Finland.;Faculty of Medicine, Center for Life Course Health Research, University of Oulu, Oulu, Finland.
[105]
Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, 2000, Denmark.
[106]
Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK.
[107]
COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
[108]
Institute of Genetic Epidemiology, Helmholtz Center Munich, German Research Center for Environmental Health, German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
[109]
Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore, 117549, Singapore.;Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.;Duke-NUS Medical School, Singapore, 169857, Singapore.
[110]
Department of Medicine, University of Leipzig, Leipzig, 04103, Germany.
[111]
Anogia Medical Centre, Anogia, Greece.
[112]
Folkhälsan Research Centre, Helsinki, Finland.;Department of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland.;Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.;Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.
[113]
Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, FI-00271, Finland.;Department of Public Health, University of Helsinki, Helsinki, Finland.;Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
[114]
Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, 70210, Finland.
[115]
PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.;Department of Welfare, Children, Adolescents and Families Unit, National Institute for Health and Welfare, Oulu, Finland.
[116]
Italian National Research Council, Institute of Genetics and Biomedic Research, Cittadella Universitaria, Monserrato, 09042, Italy.
[117]
Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA.
[118]
INSERM U1018, Centre de recherche en Épidémiologie et Santé des Populations (CESP), Villejuif, France.
[119]
Department of Medicine, University of Leipzig, Leipzig, 04103, Germany.;Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG), Helmholtz Zentrum München, University of Leipzig and University Hospital Leipzig, Leipzig, Germany.
[120]
Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, 14558, Germany.
[121]
The Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas, 77030, USA.
[122]
The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, 10069, USA.
[123]
Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, W2 1PG, UK.;Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UB1 3HW, UK.;Imperial College Healthcare NHS Trust, London, W12 0HS, UK.
[124]
Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.;Harvard School of Medicine, Boston, MA, USA.;Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
[125]
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 169856, Singapore.;Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore.;Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.
[126]
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.;Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, MD, USA.
[127]
Department of Vascular Surgery, Division of Surgical Specialties, University Medical Center Utrecht, Utrecht, 3584 CX, The Netherlands.
[128]
Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, 17671, Greece.
[129]
William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.;Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.
[130]
Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands.
[131]
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.;Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.
[132]
CNR Institute of Clinical Physiology, Department of Clinical & Experimental Medicine, University of Pisa, Pisa, Italy.
[133]
German Center for Diabetes Research (DZD), München-Neuherberg, 85764, Germany.;Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Munich, Germany.
[134]
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark.;Faculty of Health Sciences, University of Southern Denmark, Odense, 5000, Denmark.
[135]
University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK.
[136]
Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, 02115, USA.;Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.;Departments of Pediatrics and Genetics, Harvard Medical School, Boston, MA, 02115, USA.
[137]
Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.;Stanford Cardiovascular Institute, Stanford University, Stanford, CA, 94305, USA.;Stanford Diabetes Research Center, Stanford University, Stanford, 94305, USA.
[138]
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OX3 7LE, UK.;Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, OX3 7LE, UK.
[139]
Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, CB1 8RN, UK.
[140]
Pediatric Research Center, Department of Women & Child Health, University of Leipzig, Leipzig, Germany.
[141]
Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UB1 3HW, UK.;Imperial College Healthcare NHS Trust, London, W12 0HS, UK.;National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK.
[142]
Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland.;Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, 70029, Finland.;Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, 70211, Finland.
[143]
Department of Medical Sciences, Molecular Epidemiology; EpiHealth, Uppsala University, Uppsala, 75185, Sweden.
[144]
Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.;The Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, OX3 7BN, UK.
[145]
Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, 2000, Denmark.;Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark.
[146]
Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, 48201-1928, USA.;Department of Neurology, Wayne State University School of Medicine, Detroit, MI, USA.
[147]
Department of Epidemiology & Prevention, Division of Public Health Sciences, Wake Forest University, Winston-Salem, NC, 27157, USA.
[148]
The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, 10069, USA.;The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, 10069, USA.
[149]
Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA.
[150]
Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH16 4UX, UK.
[151]
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Foresterhill Health Campus, Aberdeen, AB25 2ZD, UK.
[152]
British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TA, UK.
[153]
Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, DD2 4BF, UK.
[154]
Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands.;Laboratory of Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, 3584 CX, The Netherlands.
[155]
Faculty of Medicine, University of Split, Split, Croatia.
[156]
Cardiovascular Health Research Unit, University of Washington, Seattle, WA, 98195, USA.;Department of Medicine, University of Washington, Seattle, WA, USA.;Departments of Epidemiology, Health Systems and Population Health, University of Washington, Seattle, Seattle, WA, USA.
[157]
Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.;Harvard School of Medicine, Boston, MA, USA.;Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.
[158]
Department of Public Health & Clinical Medicine, Section for Family Medicine, Umeå University, Umeå, SE-901 85, Sweden.
[159]
Department of Medicine, McGill University, Montreal, Quebec, H4A 3J1, Canada.;Department of Human Genetics, McGill University, Montreal, Quebec, H3A 1B1, Canada.
[160]
Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.;Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, EH8 9JZ, UK.
[161]
Institute of Cellular Medicine, The Medical School, Newcastle University, Newcastle, NE2 4HH, UK.
[162]
Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA.
[163]
Department of Human Genetics, Wellcome Sanger Institute, Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.;Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.;Technical University of Munich (TUM) and Klinikum Rechts der Isar, TUM School of Medicine, Munich, Germany.
[164]
Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, University of Manchester, Manchester, UK.
[165]
Department of Medicine, Harvard Medical School, Boston, MA, USA.;Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.;Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA.
[166]
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OX3 7LE, UK.;Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.;Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, OX3 7LE, UK.;Current address: Genentech, South San Francisco, CA, 94080, USA.
[167]
Division of General Internal Medicine, Massachusetts General Hospital, Department of Medicine, Harvard Medical School, Boston, MA, USA.;Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA.
[168]
Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.;Current address: Genentech, South San Francisco, CA, 94080, USA.
[169]
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OX3 7LE, UK.;Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.;Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, OX3 7LE, UK.;Division of Endocrinology, Department of Pediatrics, Stanford School of Medicine, Stanford, CA, USA.
[170]
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.;Department of Human Genetics, Wellcome Sanger Institute, Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.;Exeter Centre of Excellence in Diabetes (EXCEED), University of Exeter Medical School, Exeter, UK.
[171]
DOI
10.12688/wellcomeopenres.18754.1
PMID
39280063
发布时间
2025-07-21
- 浏览1
Wellcome open research
Wellcome open research
2023年8卷
483页
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