换一批
换一批Upregulation of Phosphodiesterase 7A Contributes to Concurrent Pain and Depression via Inhibition of cAMP-PKA-CREB-BDNF Signaling and Neuroinflammation in the Hippocampus of Mice.
作者：
主题词
动物(Animals);男(雄)性(Male);小鼠(Mice);脑源性神经营养因子(Brain-Derived Neurotrophic Factor);环AMP(Cyclic AMP);cAMP反应元件结合蛋白质(Cyclic AMP Response Element-Binding Protein);环AMP依赖性蛋白激酶类(Cyclic AMP-Dependent Protein Kinases);环核苷酸磷酸二酯酶类, 7型(Cyclic Nucleotide Phosphodiesterases, Type 7);抑郁(Depression);疾病模型, 动物(Disease Models, Animal);海马(Hippocampus);小鼠, 近交C57BL(Mice, Inbred C57BL);神经痛(Neuralgia);磷酸二酯酶抑制剂(Phosphodiesterase Inhibitors);信号传导(Signal Transduction);三嗪类(Triazines);增量调节(Up-Regulation)
DOI
10.1093/ijnp/pyae040
PMID
39283715
发布时间
2024-10-28
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