首页> Hepatobiliary & pancreatic diseases international : HBPD INT> Fibrotic liver extracellular matrix induces cancerous phenotype in biomimetic micro-tissues of hepatocellular carcinoma model.

Fibrotic liver extracellular matrix induces cancerous phenotype in biomimetic micro-tissues of hepatocellular carcinoma model.

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第一作者： Kosar,Nouri

第一单位： Department of Developmental Biology, University of Science and Culture, ACECR 14155-4364 Tehran, Iran; Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR 14155-4364 Tehran, Iran; Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR 14155-4364 Tehran, Iran.

作者： Kosar,Nouri ^[1] ; Abbas,Piryaei ^[2] ; Homeyra,Seydi ^[1] ; Ibrahim,Zarkesh ^[3] ; Ibrahim,Ghoytasi ^[4] ; Bahare,Shokouhian ^[5] ; Mustapha,Najimi ^[6] ; Massoud,Vosough ^[7]

作者单位： Department of Developmental Biology, University of Science and Culture, ACECR 14155-4364 Tehran, Iran; Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR 14155-4364 Tehran, Iran; Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR 14155-4364 Tehran, Iran. ^[1] Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. ^[2] Department of Cell Engineering, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR 14155-4364 Tehran, Iran. ^[3] Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR 14155-4364 Tehran, Iran. ^[4] Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR 14155-4364 Tehran, Iran; Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. ^[5] Laboratory of Pediatric Hepatology and Cell Therapy, Institute of Experimental and Clinical Research (IREC), UCLouvain, Brussels, Belgium. ^[6] Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR 14155-4364 Tehran, Iran; Experimental Cancer Medicine, Institution for Laboratory Medicine, Karolinska Institute, Stockholm, Sweden. Electronic address: masvos@royaninstitute.org. ^[7]

关键词 Cell differentiation Decellularized extracellular matrix Epithelial-to-mesenchymal transition Hepatocellular carcinoma Liver fibrosis Spheroid