Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA).

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第一作者： Mengqi,Wang

第一单位： Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

作者： Mengqi,Wang ^[1] ; Masood,Kamali-Moghaddam ^[2] ; Liza,Löf ^[2] ; Matilde,Cortabarría Fernandez ^[3] ; Roger,Díaz Codina ^[1] ; Fredrik H,Sterky ^[4] ; Mikael,Åberg ^[5] ; Ulf,Landegren ^[6] ; Hongxing,Zhao ^[7]

作者单位： Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. ^[1] Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.;Unit of Affinity Proteomics Uppsala, Science for Life Laboratory, Uppsala, Sweden. ^[2] Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.;Institut Pasteur de Montevideo, Montevideo, Uruguay. ^[3] Department of Laboratory Medicine, University of Gothenburg, Gothenburg, Sweden.;Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.;Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden. ^[4] Unit of Affinity Proteomics Uppsala, Science for Life Laboratory, Uppsala, Sweden.;Department of Medical Sciences, Uppsala University, Uppsala, Sweden. ^[5] Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. ulf.landegren@igp.uu.se. ^[6] Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. Hongxing.zhao@igp.uu.se.;Unit of Affinity Proteomics Uppsala, Science for Life Laboratory, Uppsala, Sweden. Hongxing.zhao@igp.uu.se. ^[7]

关键词 Antibody isotypes Antibody proximity extension assay Dried blood spot (DBS)Dried saliva spot (DSS)IgA IgG IgM Immunoassays Real-time PCR SARS-CoV-2 antibody Vaccination

主题词人类(Humans);唾液(Saliva);免疫球蛋白M(Immunoglobulin M);免疫球蛋白G(Immunoglobulin G);免疫球蛋白A(Immunoglobulin A);抗体, 病毒(Antibodies, Viral)

DOI 10.1038/s41598-024-72453-5

PMID 39289450

发布时间 2024-09-20

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准确一般字义偏差语意偏离译文作用小提交