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Colchicine treatment in amyotrophic lateral sclerosis: safety, biological and clinical effects in a randomized clinical trial.

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作者单位: Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena 41121, Italy.;Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena 41126, Italy. [1] Unit of Statistical and Methodological Support to Clinical Research, Azienda Ospedaliero-Universitaria, Modena 41121, Italy. [2] Dipartimento di Scienze Farmacologiche e Biomolecolari 'Rodolfo Paoletti', Università degli Studi di Milano, Milan 20122, Italy.;Dipartimento di Eccellenza 2018-2027, Università degli Studi di Milano, Milan 20122, Italy. [3] Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena 41121, Italy. [4] Research Center for ALS, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan 20156, Italy. [5] Cellular Model and Neuroepigenetics Unit, IRCCS Mondino Foundation, Pavia 27100, Italy. [6] Department of Pediatrics, Center of Functional Genomics and Rare diseases, 'V. Buzzi' Children's Hospital, Milan 20154, Italy. [7] Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena 41126, Italy.;Neurosciences PhD Program, University of Modena and Reggio Emilia, Modena 41121, Italy. [8] Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena 41126, Italy.;Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena 41121, Italy. [9] Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena 41126, Italy. [10] Department of Advanced Medical and Surgical Sciences, ALS Center, Università degli Studi della Campania L. Vanvitelli, Naples 80138, Italy. [11] Department of Neurology, IRCCS Istituto Auxologico Italiano, Milan 20149, Italy.;Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan 20122, Italy. [12] Department of Neurology, IRCCS Istituto Auxologico Italiano, Milan 20149, Italy. [13] Neuroncology and Neuroinflammation Unit, IRCCS Mondino Foundation, Pavia 27100, Italy. [14] Department of Aging, Neurological, Orthopedic and Head-Neck Sciences, Adult NEMO Clinical Center, Unit of Neurology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome 00168, Italy. [15] 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan 20133, Italy. [16] Department of Basic Medical Sciences, ALS Center, Neurosciences and Sense Organs, University of Bari, Bari 70124, Italy. [17] Unit of Statistical and Methodological Support to Clinical Research, Azienda Ospedaliero-Universitaria, Modena 41121, Italy.;Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena 41124, Italy. [18]
DOI 10.1093/braincomms/fcae304
PMID 39291166
发布时间 2024-09-19
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Brain communications

Brain communications

2024年6卷5期

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