Hybrid nanoparticle-mediated simultaneous ROS scavenging and STING activation improve the antitumor immunity of in situ vaccines.

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作者： Jianing,Li ^[1] ; Tianze,Wu ^[1] ; Weidong,Wang ^[1] ; Yimin,Gong ^[1] ; Mingzhu,Lu ^[1] ; Mengmeng,Zhang ^[1] ; Wanyue,Lu ^[1] ; Yaming,Zhou ^[1] ; Yannan,Yang ^[2]

作者单位： Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai 200433, China. ^[1] Institute of Optoelectronics, Fudan University, Shanghai 200433, China.;South Australian immunoGENomics Cancer Institute, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia 5005, Australia. ^[2]

主题词活性氧(Reactive Oxygen Species);动物(Animals);纳米粒子(Nanoparticles);小鼠(Mice);癌症疫苗(Cancer Vaccines);树突细胞(Dendritic Cells);肿瘤微环境(Tumor Microenvironment);膜蛋白质类(Membrane Proteins);人类(Humans);肿瘤(Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);免疫疗法(Immunotherapy);自由基清除剂(Free Radical Scavengers)

DOI 10.1126/sciadv.adn3002

PMID 39292792

发布时间 2024-09-25

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Science advances

2024年10卷38期

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Hybrid nanoparticle-mediated simultaneous ROS scavenging and STING activation improve the antitumor immunity of in situ vaccines.

Science advances

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Hybrid nanoparticle-mediated simultaneous ROS scavenging and STING activation improve the antitumor immunity of in situ vaccines.

Science advances

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