Transcriptomic signatures during normothermic liver machine perfusion correspond with graft quality and predict the early graft function.

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第一作者： Theresa,Hautz

第一单位： OrganLife Organ Regeneration Centre of Excellence and Daniel Swarovski Research Laboratory (DSL), Department of Visceral, Transplant and Thoracic Surgery, Centre of Operative Medicine, Medical University of Innsbruck, Anichstr. 35, A-6020, Innsbruck, Austria. Electronic address: Theresa.hautz@i-med.ac.at.

作者： Theresa,Hautz ^[1] ; Hubert,Hackl ^[2] ; Hendrik,Gottschling ^[3] ; Raphael,Gronauer ^[2] ; Julia,Hofmann ^[3] ; Stefan,Salcher ^[4] ; Bettina,Zelger ^[5] ; Rupert,Oberhuber ^[3] ; Benno,Cardini ^[3] ; Annemarie,Weissenbacher ^[3] ; Thomas,Resch ^[3] ; Jakob,Troppmair ^[3] ; Stefan,Schneeberger ^[3]

作者单位： OrganLife Organ Regeneration Centre of Excellence and Daniel Swarovski Research Laboratory (DSL), Department of Visceral, Transplant and Thoracic Surgery, Centre of Operative Medicine, Medical University of Innsbruck, Anichstr. 35, A-6020, Innsbruck, Austria. Electronic address: Theresa.hautz@i-med.ac.at. ^[1] Institute of Bioinformatics, Biocentre, Medical University of Innsbruck, Innrain 80/82, A-6020, Innsbruck, Austria. ^[2] OrganLife Organ Regeneration Centre of Excellence and Daniel Swarovski Research Laboratory (DSL), Department of Visceral, Transplant and Thoracic Surgery, Centre of Operative Medicine, Medical University of Innsbruck, Anichstr. 35, A-6020, Innsbruck, Austria. ^[3] Department of Internal Medicine V, Haematology and Oncology, Comprehensive Cancer Centre Innsbruck (CCCI), Medical University of Innsbruck, Anichstr. 35, A-6020, Innsbruck, Austria. ^[4] Institute of Pathology, Medical University of Innsbruck, Muellerstr. 44, A-6020, Innsbruck, Austria. ^[5]

关键词 Gene expression Inflammation Ischemia-reperfusion injury Liver Normothermic machine perfusion Transplantation

主题词肝移植(Liver Transplantation);人类(Humans);灌流(Perfusion);肝(Liver);男(雄)性(Male);女(雌)性(Female);中年人(Middle Aged);基因表达谱(Gene Expression Profiling);器官保存(Organ Preservation);成年人(Adult);再灌注损伤(Reperfusion Injury);老年人(Aged);移植物存活(Graft Survival);基因表达调控(Gene Expression Regulation)

DOI 10.1016/j.ebiom.2024.105330

PMID 39299005

发布时间 2024-10-11

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Transcriptomic signatures during normothermic liver machine perfusion correspond with graft quality and predict the early graft function.

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Transcriptomic signatures during normothermic liver machine perfusion correspond with graft quality and predict the early graft function.

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