Lidocaine combined with general anesthetics impedes metastasis of breast cancer cells via inhibition of TGF-β/Smad-mediated EMT signaling by reprogramming tumor-associated macrophages.

导出 LinkOut

翻译打印收藏纠错

作者： Beom,Seok Han ^[1] ; Soyeon,Ko ^[1] ; Min,Seok Park ^[1] ; Yun,Ji Lee ^[1] ; Sang,Eun Kim ^[1] ; Pureunchowon,Lee ^[1] ; Ye,Jin Cho ^[1] ; Han,Gyeol Go ^[1] ; Sehan,Kwak ^[1] ; Eunji,Park ^[1] ; Ayoung,Lim ^[1] ; Suji,Lee ^[1] ; Seungjong,Yoo ^[2] ; Hyunzu,Kim ^[3] ; Kyung,Hee Jung ^[4] ; Soon-Sun,Hong ^[5]

作者单位： Department of Biomedical Sciences, College of Medicine, and Program in Biomedical Science & Engineering, Inha University, 366, Seohae-daero, Jung-gu, Incheon 22332, Republic of Korea. ^[1] Department of Anesthesiology and Pain Medicine, Inha University, 366, Seohae-daero, Jung-gu, Incheon 22332, Republic of Korea. ^[2] Department of Anesthesiology and Pain Medicine, Inha University, 366, Seohae-daero, Jung-gu, Incheon 22332, Republic of Korea. Electronic address: aneshyunzu@gmail.com. ^[3] Department of Biomedical Sciences, College of Medicine, and Program in Biomedical Science & Engineering, Inha University, 366, Seohae-daero, Jung-gu, Incheon 22332, Republic of Korea. Electronic address: jkh2261@inha.ac.kr. ^[4] Department of Biomedical Sciences, College of Medicine, and Program in Biomedical Science & Engineering, Inha University, 366, Seohae-daero, Jung-gu, Incheon 22332, Republic of Korea. Electronic address: hongs@inha.ac.kr. ^[5]

关键词 Breast cancer EMT pathway General anesthetics Lidocaine TAM