Oral decitabine/cedazuridine versus intravenous decitabine for acute myeloid leukaemia: A randomised, crossover, registration, pharmacokinetics study.

导出 LinkOut

翻译打印收藏纠错

第一作者： Klaus,Geissler

第一单位： Sigmund Freud PrivatUniversität, Wien, Austria.

作者： Klaus,Geissler ^[1] ; Zdenek,Koristek ^[2] ; Teresa Bernal,Del Castillo ^[3] ; Jan,Novák ^[4] ; Gabriela,Rodríguez-Macías ^[5] ; Stephan K,Metzelder ^[6] ; Arpad,Illes ^[7] ; Jiří,Mayer ^[8] ; Montserrat,Arnan ^[9] ; Mary-Margaret,Keating ^[10] ; Jürgen,Krauter ^[11] ; Monia,Lunghi ^[12] ; Nicola Stefano,Fracchiolla ^[13] ; Uwe,Platzbecker ^[14] ; Valeria,Santini ^[15] ; Yuri,Sano ^[16] ; Aram,Oganesian ^[16] ; Harold,Keer ^[16] ; Michael,Lübbert ^[17]

作者单位： Sigmund Freud PrivatUniversität, Wien, Austria. ^[1] Department of Haematooncology, University Hospital Ostrava, Ostrava, Czech Republic. ^[2] Hospital Universitario Central de Asturias, Instituo de Investigación Sanitaria del Principado de Asturias, Instituto Universitario de Oncología del Principado de Asturias, Oviedo, Spain. ^[3] Department of Haematology, Third Faculty of Medicine, Charles University and Faculty Hospital University, Hospital Královské Vinohrady, Prague, Czech Republic. ^[4] Hospital General Universitario Gregorio Marañón, Madrid, Spain. ^[5] Philipps University Marburg and University Hospital Gießen and Marburg, Marburg, Germany. ^[6] Division of Hematology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Hungary. ^[7] Fakultní Nemocnice Brno and Masaryk University, Brno, Czech Republic. ^[8] Institut Català d'Oncologia-Hospital Duran i Reynals, Barcelona, Spain. ^[9] Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada. ^[10] Städtisches Klinikum Braunschweig, Klinik für Hämatologie und Onkologie, Braunschweig, Germany. ^[11] Azienda Ospedaliero-Universitaria Maggiore Della Carità Novara, Novara, Italy. ^[12] Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, SC Ematologia, Milan, Italy. ^[13] Universitätsklinikum Leipzig, Leipzig, Germany. ^[14] MDS Unit, Hematology, AOUC, DMSC, Università degli Studi di Firenze, Firenze, Italy. ^[15] Taiho Oncology, Inc., Pleasanton, California, USA. ^[16] Department of Haematology, Oncology, and Stem Cell Transplantation, University of Freiburg Medical Center, University of Freiburg Faculty of Medicine, Freiburg, Germany. ^[17]

关键词 DNA methyltransferase inhibitors acute myeloid leukaemia decitabine/cedazuridine hypomethylating agents somatic mutations