Impact of Chromatin Organization and Epigenetics on CRISPR-Cas and TALEN Genome Editing.

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第一作者： Surbhi,Jain

第一单位： Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.

作者： Surbhi,Jain ^[1] ; Guanhua,Xun ^[2] ; Huimin,Zhao ^[3]

作者单位： Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States. ^[1] Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.;Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States. ^[2] Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.;Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.;Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.;Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.;DOE Center for Advanced Bioenergy and Bioproducts Innovation, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States. ^[3]

关键词 CRISPR-Cas and TALEN genome editors Chromatin engineering Epigenetic editing Genome editing Genome search mechanism

主题词染色质(Chromatin);人类(Humans);后成说, 遗传(Epigenesis, Genetic);DNA(DNA)

DOI 10.1021/acssynbio.4c00099

PMID 39315937

发布时间 2024-10-18

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