Local anesthetic tetracaine hydrochloride induces pyroptosis via caspase-3/gasdermin E in uveal melanoma.

导出 LinkOut

翻译打印收藏纠错

第一作者： Peng,Yi

第一单位： Department of Anesthesiology, the Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China; Anesthesiology and Critical Care Medicine Key Laboratory of Luzhou, the Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China.

作者： Peng,Yi ^[1] ; Ran,Zhang ^[2] ; Zhengshan,Qin ^[1] ; Xin,Zhao ^[1] ; Chunyi,Wu ^[1] ; Yajun,Yu ^[3] ; Li,Liu ^[1] ; Jianlong,Zhou ^[4] ; Jianguo,Feng ^[5]

作者单位： Department of Anesthesiology, the Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China; Anesthesiology and Critical Care Medicine Key Laboratory of Luzhou, the Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China. ^[1] Department of Anesthesiology, the Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China; Anesthesiology and Critical Care Medicine Key Laboratory of Luzhou, the Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China; Department of Anesthesiology, Suining Central Hospital, Suining, Sichuan 629000, China. ^[2] Key Laboratory of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research and Institute of Metabolic Diseases, Southwest Medical University, Luzhou, Sichuan 646000, China. ^[3] Department of Oncology, Guangxi International Zhuang Medicine Hospital, Nanning, Guangxi, China. Electronic address: 303050757@qq.com. ^[4] Department of Anesthesiology, the Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China; Anesthesiology and Critical Care Medicine Key Laboratory of Luzhou, the Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China. Electronic address: fengjianguo@swmu.edu.cn. ^[5]

关键词 Gasdermin E (GSDME)Local anesthetics Pyroptosis Tetracaine hydrochloride Uveal melanoma