Disruption of the intestinal clock drives dysbiosis and impaired barrier function in colorectal cancer.

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第一作者： Rachel C,Fellows

第一单位： Department of Biological Chemistry, University of California Irvine, Irvine, CA 92697, USA.

作者： Rachel C,Fellows ^[1] ; Sung Kook,Chun ^[1] ; Natalie,Larson ^[1] ; Bridget M,Fortin ^[1] ; Alisa L,Mahieu ^[1] ; Wei A,Song ^[1] ; Marcus M,Seldin ^[2] ; Nicholas R,Pannunzio ^[3] ; Selma,Masri ^[1]

作者单位： Department of Biological Chemistry, University of California Irvine, Irvine, CA 92697, USA. ^[1] Department of Biological Chemistry, University of California Irvine, Irvine, CA 92697, USA.;Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, 92697, USA. ^[2] Department of Biological Chemistry, University of California Irvine, Irvine, CA 92697, USA.;Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, 92697, USA.;Department of Medicine, Division of Hematology/Oncology, University of California Irvine, Irvine, CA 92697, USA. ^[3]

主题词动物(Animals);结直肠肿瘤(Colorectal Neoplasms);小鼠(Mice);昼夜节律钟(Circadian Clocks);肠黏膜(Intestinal Mucosa);疾病模型, 动物(Disease Models, Animal);人类(Humans);通透性(Permeability)

DOI 10.1126/sciadv.ado1458

PMID 39331712

发布时间 2024-12-12

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Science advances

2024年10卷39期

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Disruption of the intestinal clock drives dysbiosis and impaired barrier function in colorectal cancer.

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Disruption of the intestinal clock drives dysbiosis and impaired barrier function in colorectal cancer.

Science advances

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