Mannitol-Coated Hydroxypropyl Methylcellulose as a Directly Compressible Controlled Release Excipient for Moisture-Sensitive Drugs: A Stability Perspective.

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作者： Christina Yong Xin,Kang ^[1] ; Keat Theng,Chow ^[2] ; Yuan Siang,Lui ^[2] ; Antoine,Salome ^[3] ; Baptiste,Boit ^[3] ; Philippe,Lefevre ^[3] ; Tze Ning,Hiew ^[4] ; Rajeev,Gokhale ^[5] ; Paul Wan Sia,Heng ^[4]

作者单位： Roquette Asia Pacific Pte. Ltd., 11 Biopolis Way, Helios, #05-06, Singapore 138667, Singapore.;GEA-NUS Pharmaceutical Processing Research Laboratory, Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore. ^[1] Roquette Asia Pacific Pte. Ltd., 11 Biopolis Way, Helios, #05-06, Singapore 138667, Singapore. ^[2] Roquette Frères, 1 Rue de la Haute Loge, 62136 Lestrem, France. ^[3] GEA-NUS Pharmaceutical Processing Research Laboratory, Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore. ^[4] Roquette America Inc., 2211 Innovation Drive, Geneva, IL 60134, USA. ^[5]

关键词 aspirin co-processed hydroxypropyl methylcellulose mannitol stability

DOI 10.3390/ph17091167

PMID 39338330

发布时间 2024-09-30

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