Human salivary histatin 1 regulating IP3R1/GRP75/VDAC1 mediated mitochondrial-associated endoplasmic reticulum membranes (MAMs) inhibits cell senescence for diabetic wound repair.

导出 LinkOut

翻译打印收藏纠错

作者： Tinghui,Xian ^[1] ; Yi,Liu ^[2] ; Yongsheng,Ye ^[3] ; Bohua,Peng ^[4] ; Jie,Huang ^[4] ; Lin,Liang ^[4] ; Jiaqing,Zhang ^[5] ; Hao,Wu ^[4] ; Zhen,Lin ^[4]

作者单位： Department of Biochemistry and Molecular Biology, School of Preclinical Medicine, Jinan University, 601 West Huangpu Avenue, Guangzhou, Guangdong, 510632, China. Electronic address: 18565347912@163.com. ^[1] Department of Oral Implantology, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China. ^[2] Department of Bone and Joint Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510632, China; Department of Orthopedics, Dongguan Hospital of Traditional Chinese Medicine, Dongcheng District, Dongguan, Guangdong, 523000, China. ^[3] Department of Orthopaedics, The First Affiliated Hospital of Jinan University, No. 613 11 West Huangpu Avenue, Tianhe District, Guangzhou, Guangdong, 510630, China. ^[4] Department of Biochemistry and Molecular Biology, School of Preclinical Medicine, Jinan University, 601 West Huangpu Avenue, Guangzhou, Guangdong, 510632, China. ^[5]

关键词 Cell senescence Hst1 IP3R1/GRP75/VDAC1 complex Mitochondria-associated ER membranes Mitochondrial function Oxidative stress