Alleviation of Copper-Induced Hepatotoxicity by Bergenin: Diminution of Oxidative Stress, Inflammation, and Apoptosis via Targeting SIRT1/FOXO3a/NF-κB Axes and p38 MAPK Signaling.

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第一作者： Samyah T,Alanazi

第一单位： Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, 11433, Riyadh, Saudi Arabia.

作者： Samyah T,Alanazi ^[1] ; Samir A,Salama ^[2] ; Musaad M,Althobaiti ^[3] ; Rana A,Alotaibi ^[4] ; Ammar A,AlAbdullatif ^[5] ; Arafa,Musa ^[6] ; Gamaleldin I,Harisa ^[7]

作者单位： Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, 11433, Riyadh, Saudi Arabia. ^[1] Division of Biochemistry, Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, 21944, Taif, Saudi Arabia. s.salama@tu.edu.sa. ^[2] Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, 21944, Taif, Saudi Arabia. ^[3] College of Pharmacy, Taif University, P.O. Box 11099, 21944, Taif, Saudi Arabia. ^[4] Pharmaceutical Care Services, Ministry of the National Guard-Health Affairs, P.O. Box 4616, 31412, Dammam, Saudi Arabia. ^[5] Department of Pharmacognosy, College of Pharmacy, Jouf University, 72341, Sakaka, Aljouf, Saudi Arabia. ^[6] Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, 11451, Riyadh, Saudi Arabia. ^[7]

关键词 Bergenin Copper FOXO3a Hepatotoxicity SIRT1 Wilson’s Disease

DOI 10.1007/s12011-024-04401-3

PMID 39347884

发布时间 2024-09-30

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Alleviation of Copper-Induced Hepatotoxicity by Bergenin: Diminution of Oxidative Stress, Inflammation, and Apoptosis via Targeting SIRT1/FOXO3a/NF-κB Axes and p38 MAPK Signaling.

Biological trace element research

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Alleviation of Copper-Induced Hepatotoxicity by Bergenin: Diminution of Oxidative Stress, Inflammation, and Apoptosis via Targeting SIRT1/FOXO3a/NF-κB Axes and p38 MAPK Signaling.

Biological trace element research

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Biological trace element research

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