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Single-cell phenotypic profiling and backtracing exposes and predicts clinically relevant subpopulations in isogenic Staphylococcus aureus communities.

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第一作者： Jonathan,Hira

第一单位： Centre for New Antibacterial Strategies (CANS) and Research Group for Host-Microbe Interactions, Department of Medical Biology, UiT - The Arctic University of Norway, Tromsø, Norway.

作者： Jonathan,Hira ^[1] ; Bhupender,Singh ^[1] ; Tirthankar,Halder ^[1] ; Anel,Mahmutovic ^[2] ; Clement,Ajayi ^[1] ; Arif Ahmed,Sekh ^[3] ; Kristin,Hegstad ^[4] ; Mona,Johannessen ^[1] ; Christian S,Lentz ^[5]

作者单位： Centre for New Antibacterial Strategies (CANS) and Research Group for Host-Microbe Interactions, Department of Medical Biology, UiT - The Arctic University of Norway, Tromsø, Norway. ^[1] Early Biometrics & Statistical Innovation Data Science & AI AstraZeneca, Biopharmaceuticals RD AstraZeneca, Mölndal, Sweden. ^[2] XIM University, Bhubaneshwar, India. ^[3] Centre for New Antibacterial Strategies (CANS) and Research Group for Host-Microbe Interactions, Department of Medical Biology, UiT - The Arctic University of Norway, Tromsø, Norway.;Norwegian National Advisory Unit on Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway. ^[4] Centre for New Antibacterial Strategies (CANS) and Research Group for Host-Microbe Interactions, Department of Medical Biology, UiT - The Arctic University of Norway, Tromsø, Norway. christian.s.lentz@uit.no. ^[5]

医学主题词金黄色葡萄球菌(Staphylococcus aureus);单细胞分析(Single-Cell Analysis);表型(Phenotype);抗菌药(Anti-Bacterial Agents);流式细胞术(Flow Cytometry);万古霉素(Vancomycin);微生物敏感性试验(Microbial Sensitivity Tests);人类(Humans);葡萄球菌感染(Staphylococcal Infections)

DOI 10.1038/s42003-024-06894-z

PMID 39354092

发布时间 2024-10-04

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Communications biology

2024年7卷1期

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Communications biology

2024年7卷1期

1228页

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Single-cell phenotypic profiling and backtracing exposes and predicts clinically relevant subpopulations in isogenic Staphylococcus aureus communities.

Communications biology

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Single-cell phenotypic profiling and backtracing exposes and predicts clinically relevant subpopulations in isogenic Staphylococcus aureus communities.

Communications biology

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Communications biology

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