Paeonol prevents sepsis-associated encephalopathy via regulating the HIF1A pathway in microglia.

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作者： Ning,Zhang ^[1] ; Yongjie,Ma ^[1] ; Yuqing,Li ^[2] ; Yiqi,Wang ^[1] ; Lisheng,Zhang ^[1] ; Mincheng,Zheng ^[1] ; Yu,Tian ^[1] ; Ruiying,Zhang ^[1] ; Kanlin,Yang ^[1] ; Jieyuan,Li ^[1] ; Fuman,Yan ^[3] ; Haimei,Liu ^[4] ; Yaxing,Zhang ^[4] ; Jinwen,Xu ^[5] ; Cong,Yu ^[6] ; Jiean,Xu ^[7]

作者单位： Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, University Town, Guangzhou, China. ^[1] School of Pharmaceutical Science, Guangzhou University of Chinese Medicine, University Town, Guangzhou, China. ^[2] Department of Physiology, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, University Town, Guangzhou, China. ^[3] Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, University Town, Guangzhou, China; Department of Physiology, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, University Town, Guangzhou, China. ^[4] Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, University Town, Guangzhou, China; Department of Physiology, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, University Town, Guangzhou, China. Electronic address: xujinwen@gzucm.edu.cn. ^[5] Department of Neonatology, Jiangxi Provincial Children's Hospital, Nanchang, China. Electronic address: yucong_cc@163.com. ^[6] Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, University Town, Guangzhou, China; Department of Physiology, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, University Town, Guangzhou, China. Electronic address: xujiean@gzucm.edu.cn. ^[7]

关键词 HIF1A Microglia Neuroinflammation Paeonol Sepsis-associated encephalopathy