Pectolinarigenin alleviates calcium oxalate-induced renal inflammation and oxidative stress by binding to HIF-1α.

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第一作者： Rui,Yao

第一单位： Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei, China; Institute of Urology, Anhui Medical University, Hefei, China; Anhui Province Key Laboratory of Urological and Andrological Diseases Research and Medical Transformation, Hefei, China.

作者： Rui,Yao ^[1] ; Jia-Shan,Pan ^[1] ; Ruo-Bing,He ^[2] ; Bing-Bing,Hou ^[1] ; Xiao-Guo,Suo ^[2] ; Guo-Xiang,Li ^[1] ; Kai-Guo,Xia ^[1] ; De-Kai,Hu ^[1] ; Xi-Ke,Mao ^[1] ; Wei,Li ^[2] ; Zong-Yao,Hao ^[3]

作者单位： Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei, China; Institute of Urology, Anhui Medical University, Hefei, China; Anhui Province Key Laboratory of Urological and Andrological Diseases Research and Medical Transformation, Hefei, China. ^[1] Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, The Key Laboratory of Anti-inflammatory of Immune Medicines, Ministry of Education, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. ^[2] Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei, China; Institute of Urology, Anhui Medical University, Hefei, China; Anhui Province Key Laboratory of Urological and Andrological Diseases Research and Medical Transformation, Hefei, China. Electronic address: haozongyao@ahmu.edu.cn. ^[3]

关键词 Calcium oxalate HIF-1α Inflammation Nephrocalcinosis Oxidative stress Pectolinarigenin