Inhibition of HOXC11 by artesunate induces ferroptosis and suppresses ovarian cancer progression through transcriptional regulation of the PROM2/PI3K/AKT pathway.

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作者： Jun,Li ^[1] ; Lu,Feng ^[2] ; Yijun,Yuan ^[2] ; Tianwen,He ^[2] ; Xinru,Zou ^[2] ; Bin,Su ^[2] ; Kang,Liu ^[3] ; Xiaojun,Yang ^[4]

作者单位： Department of Obstetrics and Gynecology, the First Affiliated Hospital of Soochow University, Suzhou, 215006, PR China.;Department of Obstetrics and Gynecology, Nanchong Central Hospital, The Second Clinical Medical College of North Sichuan Medical College, Nanchong, Sichuan, PR China. ^[1] Department of Obstetrics and Gynecology, Nanchong Central Hospital, The Second Clinical Medical College of North Sichuan Medical College, Nanchong, Sichuan, PR China. ^[2] Institute of Tissue Engineering and Stem Cell, Nanchong Central Hospital, The Second Clinical Medical College of North Sichuan Medical College, Nanchong, Sichuan, PR China. ^[3] Department of Obstetrics and Gynecology, the First Affiliated Hospital of Soochow University, Suzhou, 215006, PR China. yang.xiaojun@hotmail.com. ^[4]

关键词 Artesunate Ferroptosis HOXC11 Ovarian cancer PI3K/AKT signaling PROM2