首页> Virology journal> Upregulation of keratin 15 is required for varicella-zoster virus replication in keratinocytes and is attenuated in the live attenuated vOka vaccine strain.

Upregulation of keratin 15 is required for varicella-zoster virus replication in keratinocytes and is attenuated in the live attenuated vOka vaccine strain.

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第一作者： Cristina,Tommasi

第一单位： Infection, Immunity and Inflammation Department, University College London GOS Institute of Child Health, London, UK.

作者： Cristina,Tommasi ^[1] ; Ohad,Yogev ^[2] ; Michael B,Yee ^[3] ; Andriani,Drousioti ^[1] ; Meleri,Jones ^[4] ; Alice,Ring ^[5] ; Manuraj,Singh ^[6] ; Inga,Dry ^[7] ; Oscar,Atkins ^[8] ; Aishath S,Naeem ^[9] ; Nisha,Kriplani ^[10] ; Arne N,Akbar ^[11] ; Jürgen G,Haas ^[10] ; Edel A,O'Toole ^[12] ; Paul R,Kinchington ^[13] ; Judith,Breuer ^[14]

作者单位： Infection, Immunity and Inflammation Department, University College London GOS Institute of Child Health, London, UK. ^[1] Infection and Immunity Department, University College London, London, UK.;Eleven Therapeutics, Cambridge, UK. ^[2] Department of Ophthalmology and of Molecular Microbiology and Genetics, University of Pittsburgh School of Medicine, Pittsburgh, US.;Krystalbio Inc, Pittsburgh, US. ^[3] Infection and Immunity Department, University College London, London, UK.;UKHSA, Porton Down, UK. ^[4] Infection and Immunity Department, University College London, London, UK. ^[5] Dermatology, St. George's Hospital, London, UK. ^[6] Infection and Immunity Department, University College London, London, UK.;The Roslin Institute, Edinburgh, UK. ^[7] Infection and Immunity Department, University College London, London, UK.;Francis Crick Institute, London, UK. ^[8] Infection and Immunity Department, University College London, London, UK.;Dana-Farber Cancer Institute, Boston, US. ^[9] Infection Medicine, University of Edinburgh, Edinburgh, UK. ^[10] Experimental & Translational Medicine, Division of Medicine, University College London, London, UK. ^[11] Centre for Cell Biology and Cutaneous Research, Blizard Institute, Queen Mary University of London, London, UK. ^[12] Department of Ophthalmology and of Molecular Microbiology and Genetics, University of Pittsburgh School of Medicine, Pittsburgh, US. ^[13] Infection, Immunity and Inflammation Department, University College London GOS Institute of Child Health, London, UK. j.breuer@ucl.ac.uk. ^[14]

关键词 IE62 KRT15 VZV vOka vaccine