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The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis.

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第一作者： Rion,Brattig-Correia

第一单位： Instituto Gulbenkian de Ciência, Oeiras, Portugal.;Department of Systems Science and Industrial Engineering, Binghamton University, New York, United States.

作者： Rion,Brattig-Correia ^[1] ; Joana M,Almeida ^[2] ; Margot Julia,Wyrwoll ^[3] ; Irene,Julca ^[4] ; Daniel,Sobral ^[5] ; Chandra Shekhar,Misra ^[6] ; Sara,Di Persio ^[7] ; Leonardo Gastón,Guilgur ^[8] ; Hans-Christian,Schuppe ^[9] ; Neide,Silva ^[8] ; Pedro,Prudêncio ^[10] ; Ana,Nóvoa ^[8] ; Ana S,Leocádio ^[8] ; Joana,Bom ^[8] ; Sandra,Laurentino ^[7] ; Moises,Mallo ^[8] ; Sabine,Kliesch ^[7] ; Marek,Mutwil ^[4] ; Luis M,Rocha ^[1] ; Frank,Tüttelmann ^[3] ; Jörg D,Becker ^[6] ; Paulo,Navarro-Costa ^[2]

作者单位： Instituto Gulbenkian de Ciência, Oeiras, Portugal.;Department of Systems Science and Industrial Engineering, Binghamton University, New York, United States. ^[1] Instituto Gulbenkian de Ciência, Oeiras, Portugal.;EvoReproMed Lab, Environmental Health Institute (ISAMB), Associate Laboratory TERRA, Faculty of Medicine, University of Lisbon, Lisbon, Portugal. ^[2] Centre of Medical Genetics, Institute of Reproductive Genetics, University and University Hospital of Münster, Münster, Germany. ^[3] School of Biological Sciences, Nanyang Technological University, Singapore, Singapore. ^[4] Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University Lisbon, Lisbon, Portugal.;UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, NOVA University Lisbon, Caparica, Portugal. ^[5] Instituto Gulbenkian de Ciência, Oeiras, Portugal.;Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal. ^[6] Centre of Reproductive Medicine and Andrology, University Hospital Münster, Münster, Germany. ^[7] Instituto Gulbenkian de Ciência, Oeiras, Portugal. ^[8] Clinic of Urology, Pediatric Urology and Andrology, Justus-Liebig-University, Giessen, Germany. ^[9] Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal. ^[10]

关键词 D. melanogaster evolutionary biology gene expression germ cells human infertility medicine meiosis mouse spermatogenesis