首页> Environmental pollution (Barking, Essex : 1987)> Exposure to PFOA, PFOS, and PFHxS induces Alzheimer's disease-like neuropathology in cerebral organoids.

Exposure to PFOA, PFOS, and PFHxS induces Alzheimer's disease-like neuropathology in cerebral organoids.

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第一作者： Shiya,Lu

第一单位： Molecular Toxicology Key Laboratory of Sichuan Provincial Education office, West China School of Public Health and West China Fourth Hospital, and State Key Laboratory of Biotherapy, Sichuan University, Chengdu, 610041, China.

作者： Shiya,Lu ^[1] ; Xizhi,Zhu ^[2] ; Pinli,Zeng ^[1] ; Linxia,Hu ^[1] ; Yan,Huang ^[1] ; Xinhua,Guo ^[1] ; Qiqi,Chen ^[1] ; Yantang,Wang ^[3] ; Li,Lai ^[4] ; Aiqin,Xue ^[4] ; Yanli,Wang ^[5] ; Zhiqiu,Wang ^[1] ; Wenbo,Song ^[4] ; Qian,Liu ^[4] ; Guohui,Bian ^[4] ; Jiayuan,Li ^[1] ; Qian,Bu ^[6] ; Xiaobo,Cen ^[7]

作者单位： Molecular Toxicology Key Laboratory of Sichuan Provincial Education office, West China School of Public Health and West China Fourth Hospital, and State Key Laboratory of Biotherapy, Sichuan University, Chengdu, 610041, China. ^[1] School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. ^[2] Department of Pharmacology, School of Pharmacy, Chengdu Medical College, Chengdu, 610500, Sichuan, China. ^[3] National Chengdu Center for Safety Evaluation of Drugs, State Key Lab of Biotherapy/Collaborative Innovation Center of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041, China. ^[4] Jinniu Maternity and Child Health Hospital of Chengdu, Chengdu, 610036, China. ^[5] Molecular Toxicology Key Laboratory of Sichuan Provincial Education office, West China School of Public Health and West China Fourth Hospital, and State Key Laboratory of Biotherapy, Sichuan University, Chengdu, 610041, China. Electronic address: buqian7978@scu.edu.cn. ^[6] National Chengdu Center for Safety Evaluation of Drugs, State Key Lab of Biotherapy/Collaborative Innovation Center of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041, China. Electronic address: xbcen@scu.edu.cn. ^[7]

关键词 Alzheimer's disease pathology Cerebral organoid Lipid disturbance PFAS mixture scRNA-seq