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首页> Cell death & disease> Inhibition of primary cilia-hedgehog signaling axis triggers autophagic cell death and suppresses malignant progression of VHL wild-type ccRCC.

Inhibition of primary cilia-hedgehog signaling axis triggers autophagic cell death and suppresses malignant progression of VHL wild-type ccRCC.

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作者： Shuo,Tian ^[1] ; Songliang,Du ^[2] ; Chenfeng,Wang ^[1] ; Yu,Zhang ^[2] ; Hanfeng,Wang ^[2] ; Yang,Fan ^[2] ; Yu,Gao ^[2] ; Liangyou,Gu ^[2] ; Qingbo,Huang ^[2] ; Baojun,Wang ^[2] ; Xin,Ma ^[3] ; Xu,Zhang ^[4] ; Yan,Huang ^[5]

作者单位： Department of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, 100853, China.;Chinese PLA Medical School, Beijing, China. ^[1] Department of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, 100853, China. ^[2] Department of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, 100853, China. mxin301@126.com.;Chinese PLA Medical School, Beijing, China. mxin301@126.com. ^[3] Department of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, 100853, China. xzhang301@163.com.;Chinese PLA Medical School, Beijing, China. xzhang301@163.com. ^[4] Department of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, 100853, China. dr.huangyan301@foxmail.com. ^[5]

主题词人类(Humans);纤毛(Cilia);癌, 肾细胞(Carcinoma, Renal Cell);信号传导(Signal Transduction);脑视网膜血管瘤抑制蛋白质(Von Hippel-Lindau Tumor Suppressor Protein);猬蛋白质类(Hedgehog Proteins);肾肿瘤(Kidney Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);动物(Animals);细胞增殖(Cell Proliferation);疾病恶化(Disease Progression);小鼠(Mice);小鼠, 裸(Mice, Nude);男(雄)性(Male);女(雌)性(Female)

DOI 10.1038/s41419-024-07085-8

PMID 39389955

发布时间 2024-10-10

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Cell death & disease

Cell death & disease

2024年15卷10期

739页

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