Low-dose aspirin and heparin treatment improves pregnancy outcome in recurrent pregnancy loss women with anti-β2-glycoprotein I/HLA-DR autoantibodies: a prospective, multicenter, observational study.

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作者： Kenji,Tanimura ^[1] ; Shigeru,Saito ^[2] ; Sayaka,Tsuda ^[2] ; Yosuke,Ono ^[3] ; Masashi,Deguchi ^[1] ; Takeshi,Nagamatsu ^[4] ; Tomoyuki,Fujii ^[5] ; Mikiya,Nakatsuka ^[6] ; Gen,Kobashi ^[7] ; Hisashi,Arase ^[8] ; Hideto,Yamada ^[9]

作者单位： Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan. ^[1] Department of Obstetrics and Gynecology, University of Toyama, Toyama, Japan. ^[2] Department of Obstetrics and Gynecology, University of Yamanashi, Yamanashi, Japan. ^[3] Department of Obstetrics and Gynecology, the University of Tokyo, Tokyo, Japan.;Department of Obstetrics and Gynecology, International University of Health and Welfare Narita Hospital, Narita, Japan. ^[4] Department of Obstetrics and Gynecology, the University of Tokyo, Tokyo, Japan.;Department of Obstetrics and Gynecology, International University of Health and Welfare Narita Hospital, Narita, Japan.;Sanno Hospital, Tokyo, Japan. ^[5] Graduate School of Health Sciences, Okayama University, Okayama, Japan. ^[6] Department of Public Health, Dokkyo Medical University School of Medicine, Tochigi, Japan. ^[7] Department of Immunochemistry, Research Institute for Microbial Disease, Osaka University, Suita, Japan. ^[8] Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan.;Center for Recurrent Pregnancy Loss, Teine Keijinkai Hospital, Sapporo, Japan. ^[9]

关键词 anti-β2-glycoprotein I/HLA-DR antibody low-dose aspirin pregnancy complications recurrent pregnancy loss treatment unfractionated heparin